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Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry
http://hdl.handle.net/10271/42
http://hdl.handle.net/10271/4227f89567-8639-4eab-99d1-25b637d40499
名前 / ファイル | ライセンス | アクション |
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JCB-832-286.pdf (448.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-08-27 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Platinum | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Electrospray ionization | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Mass spectrometry | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Diethyldithiocarbamate | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Silver | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
Minakata, Kayoko
× Minakata, Kayoko× Nozawa, Hideki× Okamoto, Naoko× Suzuki, Osamu |
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書誌情報 |
en : Journal of Chromatography B 巻 832, 号 2, p. 286-291, 発行日 2006-03-07 |
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出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | (C) Elsevier | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Determination of platinum (Pt) derived from cisplatin in tissues was performed by electrospray ionization mass spectrometry (ESI-MS) using silver (Ag) as the internal standard. Pt and Ag reacted with diethyldithiocarbamate (DDC), and were extracted using isoamylalcohol and acidified with oxalic acid. The compounds were termed Pt(DDC)3 + and Ag(DDC)2 +, based on their m/z values exhibiting the highest peaks at m/z 639 and m/z 405, respectively. The limit of detection was 30 pg and the quantitation range was from 100 to 10000 pg using 5 mg tissue. The present method allowed the determination of Pt in wet-ashed tissue in 10 minutes. | |||||
言語 | en | |||||
ISSN | ||||||
収録物識別子タイプ | PISSN | |||||
収録物識別子 | 1570-0232 | |||||
EISSN | ||||||
収録物識別子タイプ | EISSN | |||||
収録物識別子 | 1873-376X | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 16483858 | |||||
出版社DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.jchromb.2006.01.016 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |