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POSITIVE- AND NEGATIVE-ION MASS SPECTRA OF ALKYL ESTER DERIVATIVES OF COCAINE コカインとアルキルエステル類似体の正イオン・負イオンマススペクトル Kumazawa, Takeshi Watanabe, Kanako Seno, Hiroshi Ishii, Akira Sato, Keizo Suzuki, Osamu Suzuki, Kanako Copyright 日本法中毒学会 本文データは日本法中毒学会の許諾のもと掲載しています。 Cocaine Cocaethylene Cocapropylene Cocabutylene Mass Spectrometry Negative-ion chemical ionization Fragmentation pathway Positive-ion electron impact (PIEI), positive-ion chemical ionization (PICI) and negative-ion chemical ionization (NICI) mass spectra of cocaine, cocaethylene, cocapropylene and cocabutylene, were presented, and each fragmentation mode was analyzed. In the PIEI mode, molecular ions appeared for all compounds. Cations at m/z M-121, corresponding to [M-OCOC6H5]+ , constituted base peaks for all compounds. In PICI mass spectra, all compounds showed intense [M+1]+ quasi-molecular cations, which constituted base peaks, together with small peaks at m/z [M+C2H5]+ and/or [M+C3H5]+. Cations at m/z [M-OCOC6H5]+ also appeared for all compounds. In the NICI mode, anions at m/z 121, corresponding to the OCOC6H5 moiety, constituted base peaks for all compounds. To check sensitivity, the intensities of peaks obtained by total ion monitoring (TIM) were compared with each other in the three modes. The detection limits for the compounds obtained by TIM in PIEI, PICI and NICI modes with a DB-I fused silica capillary column were 11-103, 102-1300 and 185-1146 nmol on-column, respectively. 日本法中毒学会 1998-09-15 eng journal article VoR http://hdl.handle.net/10271/1719 https://hama-med.repo.nii.ac.jp/records/1686 09159606 法中毒 Japanese journal of forensic toxicology 16 3 221 227 https://hama-med.repo.nii.ac.jp/record/1686/files/FT-16-221.pdf application/pdf 264.8 kB 2018-08-27