2026-03-07T03:41:32Z https://hama-med.repo.nii.ac.jp/oai

oai:hama-med.repo.nii.ac.jp:00003744 2023-11-13T07:25:28Z 2:15:17

A Pilot Study Investigating the Use of Regional Oxygen Saturation as a Predictor of Ischemic Wound Healing Outcome after Endovascular Treatment in Patients with Chronic Limb-Threatening Ischemia 重症下肢虚血患者に対する血管内治療後、組織酸素濃度測定値の潰瘍治癒予後予測の有用性についてのパイロット研究 嘉山, 貴文 open access Copyright 2021. The Editorial Committee of Annals of Vascular Diseases. This article is distributed under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided the credit of the original work, a link to the license, and indication of any change are properly given, and the original work is not used for commercial purposes. Remixed or transformed contributions must be distributed under the same license as the original. pilot study oximetry near-infrared spectroscopy ischemia wound healing doctoral 医学系研究科 Objective: To determine the prognostic value of regional tissue oxygenation saturation (rSO2) for ulcer healing after endovascular treatment (EVT) of peripheral arterial disease (PAD). Materials and Methods: Among PAD patients, 34 patients with chronic limb-threatening ischemia underwent EVT for limb salvage. We retrospectively analyzed the cutoff rSO2 values on postoperative day 1 to predict ulcer healing and patient prognosis. Skin perfusion pressure (SPP) and transcutaneous oxygen pressure (TcPO2) were also used to assess wound healing. Results: A finger-mounted tissue oximeter can easily measure rSO2 on the dorsal foot. Among the 34 patients, the ulcer healed in 25, and no changes were observed in 2 patients at 1 month after EVT. However, 7 patients needed major amputation at the same time. Wound healing was achieved in all patients with rSO2 ≥50%. With this cutoff, the sensitivity and specificity of the new device for wound healing were 100% and 64%, respectively. In all the wound healing cases, SPP was ≥45mmHg, and TcPO2 was ≥40mmHg. Conclusion: To assess limb ischemia, rSO2 can be measured quickly and easily using this device. We suggest that an rSO2 >50% shows good prognosis for ulcer healing. The Editorial Committee of Annals of Vascular Diseases 2021-03-25 eng doctoral thesis VoR http://hdl.handle.net/10271/00003870 https://hama-med.repo.nii.ac.jp/records/3744 33786096 https://doi.org/10.3400/avd.oa.20-00132 1881-641X 1881-6428 Annals of Vascular Diseases 14 1 23 30 甲第860号 博士（医学） 2021-03-16 13802 浜松医科大学 https://hama-med.repo.nii.ac.jp/record/3744/files/DT_860ronbun.pdf application/pdf 671.5 kB 2021-08-01