2026-03-13T05:02:07Z https://hama-med.repo.nii.ac.jp/oai

oai:hama-med.repo.nii.ac.jp:02000475 2025-10-22T05:08:37Z 1:11

Extremely Poor Post-discharge Prognosis in Aspiration Pneumonia and Its Prognostic Factors: A Retrospective Cohort Study. 本田, 優希 ホンダ, ユウキ 0000000089376696 00ndx3g44 浜松医科大学 ハママツイカダイガク Hamamatsu University School of Medicine 尾島, 俊之 オジマ, トシユキ 0000000089376696 00ndx3g44 浜松医科大学 ハママツイカダイガク Hamamatsu University School of Medicine Honda, Yuki Homma, Yoichiro Nakamura, Mieko Ojima, Toshiyuki Saito, Kazuhito open access This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00455-023-10665-z aspiration pneumonia pneumonia dysphagia alternative nutrition terminal care Aim There is little evidence regarding the long-term prognosis of patients with aspiration pneumonia. This study aimed to investigate post-discharge survival time and prognostic factors in older patients hospitalized for aspiration pneumonia. Methods This retrospective cohort study included patients aged ≥65 years hospitalized for aspiration pneumonia and discharged alive from a tertiary care hospital in Japan between April 2009 and September 2014. Candidate prognostic factors were patient’s age, sex, body mass index (BMI), performance status, chronic conditions, CURB-65 score, serum albumin level, hematocrit concentration, nutritional pathway at discharge, and discharge location. Kaplan–Meier curves were determined, and multivariable survival analysis using Cox regression model was performed to analyze the effect of each factor on mortality. Results In total, 209 patients were included in this study. The median age was 85 years, 58% of the patients were males, 33% had a performance status of 4, and 34% were discharged home. Among the patients, 65% received oral intake, 23% received tube feeding, and 21% received parenteral nutrition at discharge. During the follow-up period, 77% of the patients died, and the median post-discharge survival time was 369 days. Besides male sex and low BMI, tube feeding (adjusted hazard ratio [aHR]= 1.70, 95% confidence interval [CI]:1.11–2.59) and parenteral nutrition (aHR= 4.42, 95% CI:2.57–7.60) were strongly associated with mortality. Conclusions Long-term prognosis of patients hospitalized for aspiration pneumonia was extremely poor. The nutritional pathway at discharge was a major prognostic factor. These results may be useful for future care and research. Springer Nature 2024-10 eng journal article AM http://hdl.handle.net/10271/0002000475 https://hama-med.repo.nii.ac.jp/records/2000475 38388805 https://doi.org/10.1007/s00455-023-10665-z AA10674017 1432-0460 0179-051X Dysphagia 39 5 837 845 https://hama-med.repo.nii.ac.jp/record/2000475/files/Dysphagia-39-837.pdf application/pdf 422 KB 2025-07-29