2026-03-07T08:28:00Z https://hama-med.repo.nii.ac.jp/oai

oai:hama-med.repo.nii.ac.jp:00002679 2023-10-23T07:24:32Z 2:15:17

肺動脈性肺高血圧症患者における運動耐容能評価法としての漸増シャトルウォーキングテストの有用性 Incremental shuttle walking test as a valuable assessment of exercise performance in patients with pulmonary arterial hypertension Irisawa, Hiroshi Exercise Pulmonary hypertension Rehabilitation 浜松医科大学 博士（医学） doctoral 医学系研究科 Background: Nearly all clinical trials investigating patients with pulmonary arterial hypertension (PAH) have used the 6-min walk test (6MWT) to evaluate exercise tolerance. The incremental shuttle walk test (SWT), however, has been proposed as a more valid and reproducible alternative to the 6MWT in the evaluation of exercise tolerance in patients with chronic obstructive pulmonary disease. The efficacy of SWT in clinical practice to evaluate the exercise capacity of patients with PAH was investigated. Methods and Results: The peak oxygen consumption (pV?O2) and oxygen consumption at anaerobic threshold (V?O2 at AT), the gold standard for measurement of exercise tolerance, 6MWT and SWT were measured in 19 clinically stable PAH patients (WHO functional class II-III) and the data compared. There was a higher correlation between SWT walk distance and pV?O2 than between 6MWT walk distance and pV?O2 (r=0.866 and 0.765, respectively; P<0.05), and a higher correlation between SWT walk distance and V?O2 at AT than between 6MWT walk distance and V?O2 at AT (r=0.775 and 0.587, respectively; P<0.05). No adverse events occurred during the exercise tests. Conclusions: SWT is a better reflection than 6MWT of exercise tolerance in PAH patients, and thus is a preferable alternative for assessment of exercise tolerance in PAH patients. doctoral thesis 日本循環器学会 The Japanese Circulation Society 2014-01 2014-03-17 VoR application/pdf Circulation Journal 78 215 221 甲第676号 1346-9843 1347-4820 https://hama-med.repo.nii.ac.jp/record/2679/files/DT_676ronbun.pdf http://hdl.handle.net/10271/2794 https://hama-med.repo.nii.ac.jp/records/2679 eng 130003382169 24225307 https://doi.org/10.1253/circj.CJ-13-0238 open access