{"created":"2023-06-20T15:45:36.361015+00:00","id":112,"links":{},"metadata":{"_buckets":{"deposit":"b48f76bc-f5c3-41ba-92eb-87fa4d488486"},"_deposit":{"created_by":4,"id":"112","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"112"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00000112","sets":["1:11"]},"author_link":["324"],"item_3_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"【原著】","subitem_alternative_title_language":"ja"}]},"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1991-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"488","bibliographicPageStart":"485","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"日本産科婦人科學會雜誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Acta Obstetrica et Gynaecologica Japonica","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Fibrin degradation products (FDP)の1分画であるD-dimerが卵巣癌に対する腫瘍マーカーとして有用であるか否かを検討した．血清D-dimer値ほは健常非妊婦人237±212ng/ml (N=66), 良性子宮腫瘍248±141ng/ml (N=15), 良性卵巣腫瘍299±248ng/ml (N=26), 卵巣癌721±423ng/ml (N=28)であり卵巣癌で有意にD-dimerが高値をとった．卵巣癌の組織型別D-dimer値は漿液性嚢胞腺癌840±359ng/ml (N=13), 粘液性嚢胞腺癌710±448ng/ml (N=8), その他723±340ng/ml (N=7)であり, 組織型に関係なく高値であった．cut off値を400ng/mlとすると, 卵巣癌における陽性率は79%であった．これに対してCA125, TPA, SLXおよびCEAの陽性率は, それぞれ72%, 41%, 60%および9%であった．臨床進行期別のD-dimer, CA125陽性率は, それぞれI期50%, 80%, II期88%, 67%, III期86%, 71%, IV期80%, 60%であり, D-dimerの陽性率はI期ではCA125よりも低かったがII期以上ではCA125よりも高値を示した．卵巣癌患者におけるD-dimerと他の腫瘍マーカーとの相関関係は, CA125 R=0.476, TPA R=0.376, SLX R=0.226, CEA R=-0.292で, CA125との間に弱い相関を認めたが他のマーカーとの相関関係は認められなかった．\n以上から, D-dimerは卵巣癌腫瘍マーカーとして有用であることが判明した．","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本産科婦人科学会","subitem_publisher_language":"ja"}]},"item_3_relation_22":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"110002106069","subitem_relation_type_select":"NAID"}}]},"item_3_relation_27":{"attribute_name":"医中誌論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"1992176984","subitem_relation_type_select":"ICHUSHI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(C) 日本産科婦人科学会","subitem_rights_language":"ja"},{"subitem_rights":"本文データは学協会の許諾に基づきCiNiiから複製したものである","subitem_rights_language":"ja"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0300-9165","subitem_source_identifier_type":"PISSN"}]},"item_3_source_id_23":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00190060","subitem_source_identifier_type":"NCID"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"金山, 尚裕","creatorNameLang":"ja"},{"creatorName":"KANAYAMA, Naohiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"324","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"110002106069.pdf","filesize":[{"value":"346.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110002106069.pdf","objectType":"fulltext","url":"https://hama-med.repo.nii.ac.jp/record/112/files/110002106069.pdf"},"version_id":"5c185fe2-10b3-45e7-af15-f26daf0fc1a0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Fibrin degradation product","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"D-dimer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Ovarian cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"卵巣癌腫瘍マーカーとしてのD-dimer測定の意義","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"卵巣癌腫瘍マーカーとしてのD-dimer測定の意義","subitem_title_language":"ja"},{"subitem_title":"The Role of D-dimer Diagnosis of Ovarian Cancer","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"112","relation_version_is_last":true,"title":["卵巣癌腫瘍マーカーとしてのD-dimer測定の意義"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2024-03-27T07:41:39.553824+00:00"}