{"created":"2023-06-20T15:45:37.160911+00:00","id":127,"links":{},"metadata":{"_buckets":{"deposit":"efc1cb51-1633-46ad-a11c-a79e591ee2d2"},"_deposit":{"created_by":4,"id":"127","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"127"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00000127","sets":["1:11"]},"author_link":["387","388","389","390"],"control_number":"127","item_3_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"【原著】","subitem_alternative_title_language":"ja"}]},"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1989-10-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"1506","bibliographicPageStart":"1501","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"日本産科婦人科學會雜誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Acta Obstetrica et Gynaecologica Japonica","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"卵巣癌患者を早期発見するための血清学的癌診断における腫瘍マーカーの有用性を診断効率の点から検討した．すなわち, 8種類の腫瘍マーカー, CA125, SLX, CA72-4, TPA, Fr, CEA, CA19-9, SCCを測定してどの組合せが最良の診断効率を示すかを検討した．なお, 診断効率をsensitivity×specificityにより計算した．\n単独の腫瘍マーカーではCA125の診断効率が0.50と最適であつた．2種類の腫瘍マーカーではCA125とCA72-4の組合せが診断効率0.53と最高値を示した．3種類の腫瘍マーカーではCA125, CA72-4とSLXの組合せが0.65と最良の診断効率であつた．4種類の腫瘍マーカーではCA125, CA72-4, SLX とCA19-9の組合せが診断効率0.63を示した．5種類の腫瘍マーカーではCA125, CA72-4, SLX, CA19-9とTPAの組合せが診断効率0.59を示した．6種類の腫瘍マーカーではCA125, CA72-4, SLX, CA19-9, TPAとFrの組合せが診断効率0.53を示した．7種類ではCA 125, CA 72-4, SLX, CA19-9, TPA, FrとCEAの組合せの診断効率が0.51を示した．8種類全部を組合せると診断効率は0.51と低下した．\nすなわち, 卵巣癌患者の早期発見における腫瘍マーカー測定のcost performanceを考えると, 腫瘍マーカーの種類が増えるほどsensitivityは上昇するがspecificityが低下するため, 現時点ではCA125, CA72-4, SLXの3種類の腫瘍マーカーを用いるのが診断効率の点で最良のcombination assay (sensitivity 90.3%, specificity 72.1%) であると結論できた．","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本産科婦人科学会","subitem_publisher_language":"ja"}]},"item_3_relation_22":{"attribute_name":"NII論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"110002228833","subitem_relation_type_select":"NAID"}}]},"item_3_relation_27":{"attribute_name":"医中誌論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"1990108429","subitem_relation_type_select":"ICHUSHI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(C) 日本産科婦人科学会","subitem_rights_language":"ja"},{"subitem_rights":"本文データは学協会の許諾に基づきCiNiiから複製したものである","subitem_rights_language":"ja"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0300-9165","subitem_source_identifier_type":"PISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小林, 浩","creatorNameLang":"ja"},{"creatorName":"KOBAYASHI, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"住本, 和博","creatorNameLang":"ja"},{"creatorName":"SUMITOMO, Kazuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"寺尾, 俊彦","creatorNameLang":"ja"},{"creatorName":"TERAO, Toshihiko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"川島, 吉良","creatorNameLang":"ja"},{"creatorName":"KAWASHIMA, Yoshiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"110002228833.pdf","filesize":[{"value":"590.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"110002228833.pdf","objectType":"fulltext","url":"https://hama-med.repo.nii.ac.jp/record/127/files/110002228833.pdf"},"version_id":"74c89193-2e0a-4429-904d-231cdcf96395"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Tumor marker","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Ovarian cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Serodiagnostic test","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"腫瘍マーカーを利用した卵巣癌患者の血清学的診断 ―診断効率の点から―","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腫瘍マーカーを利用した卵巣癌患者の血清学的診断 ―診断効率の点から―","subitem_title_language":"ja"},{"subitem_title":"Diagnostic Value of Serological Tumor Marker Tests in Patients with Ovarian Cancer","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"127","relation_version_is_last":true,"title":["腫瘍マーカーを利用した卵巣癌患者の血清学的診断 ―診断効率の点から―"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2024-03-27T04:10:32.699512+00:00"}