@article{oai:hama-med.repo.nii.ac.jp:00001648, author = {妹尾, 洋 and 服部, 秀樹 and 熊澤, 武志 and 鈴木, 修 and 木村, 美智子 and 山田, 高路}, issue = {2}, journal = {法中毒 = Japanese journal of forensic toxicology}, month = {Sep}, note = {Tricyclic antidepressants and local anesthetics were detected by gas chromatography (GC)-surface ionization detection (SID), which has been reported to be very sensitive and specific to tertiary amines. The detection limit in an injected volume was 5-10 pg for amitriptyline, imipramine, trimipramine, chlorimipramine, lidocaine, mepivacaine and bupivacaine, and 100-200 pg for procaine, benoxinate and dibucaine. When compared with the GC-nitrogen-phosphorus detection (NPD), the GC-SID sensitivity was 10-100 times higher, the background was cleaner, and the baseline remained steady as the column temperature was increased. The drugs could bee rapidly isolated with Sep-Pak C18 cartridges from biological fluids before GC. The recovery of the drugs was more than 60%.}, pages = {82--83}, title = {表面電離検出ガスクロマトグラフィーの法中毒学的応用}, volume = {10}, year = {1992} }