{"created":"2023-06-20T15:47:19.589700+00:00","id":1867,"links":{},"metadata":{"_buckets":{"deposit":"d4febb13-6613-4e49-86fd-2cded0c16cff"},"_deposit":{"created_by":4,"id":"1867","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"1867"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00001867","sets":["1:11"]},"author_link":["4703","4704","4705","4706","4707"],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-07-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"102","bibliographicPageStart":"98","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Forensic Toxicology","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Naphthalene is still being sold as a moth repellant; there is a possibility that accidental ingestion of such a product by a small infant causes serious poisoning. In this communication, a very simple method for analysis of naphthalene in human whole blood and urine by headspace gas chromatography (GC) has been presented. It neither needs solid-phase microextraction nor cryogenic trapping devices, but needs only a conventional capillary GC instrument with flame ionization detection. The advantage of the method is that as large as 5 ml of headspace vapor can be injected into a GC instrument in the splitless mode for sensitive detection. After heating a diluted whole blood or urine sample containing naphthalene and 1-methylnaphthalene (internal standard, IS) in a 7.0 ml vial at 80℃ for 30 min, 5 ml of the headspace vapor was drawn with a glass syringe and injected into the gas chromatograph. Before injection, the column was set at 50℃ to trap the analytes, and then the oven temperature was programmed up to 300℃. Sharp peaks were obtained for both analyte and IS, and only a few impurity peaks, which did not interfered with the test peaks, appeared especially for whole blood samples. The detection limits (signal-to-noise ratio ≧ 3) were about 0.05 and 0.01 μg/ml for whole blood and urine, respectively. Precision and linearity were also examined to confirm the reliability. Such a simple headspace GC technique with large volume injection can be probably applied also to other low-volatile compounds in biological matrices, and will be useful in forensic toxicological analysis.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s11419-009-0074-1","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright Japanese Association of Forensic Toxicology and Springer 2009","subitem_rights_language":"en"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18608965","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"18608973","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Watanabe, Kanako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4703","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hasegawa, Koutaro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4704","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamagishi, Itaru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4705","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nozawa, Hideki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4706","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4707","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"Forensic_T-27-98.pdf","filesize":[{"value":"128.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Forensic_T-27-98.pdf","url":"https://hama-med.repo.nii.ac.jp/record/1867/files/Forensic_T-27-98.pdf"},"version_id":"b8090cae-1edc-41a6-9bcd-1c5056acd862"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Naphthalene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"1-Methylnaphtalene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Gas chromatography","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Headspace sampling","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Large volume injection","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Polycyclic aromatic hydrocarbon","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Simple analysis of naphthalene in human whole blood and urine by headspace capillary gas chromatography with large volume injection","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Simple analysis of naphthalene in human whole blood and urine by headspace capillary gas chromatography with large volume injection","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"1867","relation_version_is_last":true,"title":["Simple analysis of naphthalene in human whole blood and urine by headspace capillary gas chromatography with large volume injection"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T02:07:54.492184+00:00"}