{"created":"2023-06-20T15:47:19.660979+00:00","id":1868,"links":{},"metadata":{"_buckets":{"deposit":"1a05a1d6-5869-476c-a178-5ca31d04a615"},"_deposit":{"created_by":4,"id":"1868","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"1868"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00001868","sets":["1:11"]},"author_link":["4708","4709","4710","4711","4712","4713","4714"],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-07-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"106","bibliographicPageStart":"103","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Forensic Toxicology","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A high-performance liquid chromatography (HPLC) method has been developed for the assays of five barbiturates in human urine using a new thermoresponsive polymer separation column, which is composed of N-isopropylacrylamide polymer. According to elevating the column temperature from 10 ℃ to 50 ℃, five barbiturates, such as metharbital, primidone, phenobarbital, mephobarbital and pentobarbital, became well separated by this method. Five barbiturates showed good linearity in the range of 0.2-10 mg/ml. Good accuracy, precision and recoveries for these drugs were obtained at 1 and 5 μg/ml urine. The method with the new-type column seems to have high potential to be extensively used in forensic toxicology for analysis of many drugs and poisons by HPLC and HPLC-mass spectrometry (MS) (-MS).","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s11419-009-0076-z","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright Japanese Association of Forensic Toxicology and Springer 2009","subitem_rights_language":"en"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18608965","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"18608973","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kanno, Sanae","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4708","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Watanabe, Kanako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4709","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hirano, Seishiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4710","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamagishi, Itaru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4711","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Gonmori, Kunio","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4712","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Minakata, Kayoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4713","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Suzuki, Osamu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4714","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"Forensic_T-27-103.pdf","filesize":[{"value":"208.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Forensic_T-27-103.pdf","url":"https://hama-med.repo.nii.ac.jp/record/1868/files/Forensic_T-27-103.pdf"},"version_id":"218e63d7-50d4-4701-b5a0-87d5d6ccbe66"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Thermoresponsive polymer column","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Temperature-responsive","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Barbiturates","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Phenobarbital","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HPLC","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Human urine","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Application of thermoresponsive HPLC to forensic toxicology: determination of barbiturates in human urine","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Application of thermoresponsive HPLC to forensic toxicology: determination of barbiturates in human urine","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"1868","relation_version_is_last":true,"title":["Application of thermoresponsive HPLC to forensic toxicology: determination of barbiturates in human urine"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T02:07:56.052422+00:00"}