{"created":"2024-03-07T00:47:46.974071+00:00","id":2000087,"links":{},"metadata":{"_buckets":{"deposit":"63e34279-1e84-4bc6-8837-b452bc9cf860"},"_deposit":{"created_by":4,"id":"2000087","owner":"4","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2000087"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:02000087","sets":["1:75:1709274151436"]},"author_link":[],"control_number":"2000087","item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2024-03-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"9","bibliographicPageStart":"3","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"浜松医科大学小児科学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Hamamatsu Journal of Pediatrics","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"抗菌薬の標準的な投与期間は経験則に基づいて設定されてきた．多くの場合は治療失敗を回避するために長めに設定されており，薬剤の長期投与によるデメリットは過少評価されてきた．近年，薬剤耐性菌対策の一環として，抗菌薬投与期間を短縮する試みが科学的に検証され，ランダム化比較試験や系統レビューの対象となっている．小児の一般的な感染症である，溶連菌咽頭炎，急性鼻副鼻腔炎，肺炎，尿路感染症については，有効性を損なうことなく従来の標準的な治療期間を短縮することが可能であることが確認され，各種ガイドラインにもこれが反映されつつある．その一方で，2歳未満の急性中耳炎に代表されるように，短期治療で再燃率が高まるリスク集団が存在し，適切な治療にあたっては，個別の評価が必要である．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"The standard length of antibiotic therapy has been empirically determined. In general, extensive coverage has been used to avoid treatment failures, and the risks of long-term antibiotics have been understated. The recent push to address antimicrobial resistance has resulted in scientific evaluation of antibiotic duration using randomized control trials and systematic reviews. Studies have shown that the current standard duration of antibiotics for common pediatric infectious diseases such as streptococcal pharyngitis, acute rhinosinusitis, pneumonia, and urinary tract infection can be reduced without compromising effectiveness, prompting changes in practice guidelines. In contrast, certain at-risk populations, such as children under the age of two with otitis media, experience recurrences with shorter antibiotic duration and require tailored evaluations for appropriate management.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"浜松医科大学小児科学雑誌編集部","subitem_publisher_language":"ja"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"2436-2433","subitem_source_identifier_type":"EISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"宮入, 烈","creatorNameLang":"ja"},{"creatorName":"MIYAIRI, Isao","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-03-15"}],"displaytype":"detail","filename":"hjop_4_1_3.pdf","filesize":[{"value":"564 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://hama-med.repo.nii.ac.jp/record/2000087/files/hjop_4_1_3.pdf"},"version_id":"360e1289-2a87-49ae-bece-81c31a20b51e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"咽頭炎","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"急性鼻副鼻腔炎","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"中耳炎","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"肺炎","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"尿路感染症","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"小児の一般的な感染症に対する抗菌薬投与期間","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"小児の一般的な感染症に対する抗菌薬投与期間","subitem_title_language":"ja"},{"subitem_title":"Duration of Antibiotics for Common Pediatric Infectious Diseases","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["1709274151436"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-03-15"},"publish_date":"2024-03-15","publish_status":"0","recid":"2000087","relation_version_is_last":true,"title":["小児の一般的な感染症に対する抗菌薬投与期間"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2024-03-13T01:37:32.184484+00:00"}