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Distinction between hepatocellular carcinoma and hypervascular liver metastases in non-cirrhotic patients using gadoxetate disodium-enhanced magnetic resonance imaging
http://hdl.handle.net/10271/0002000458
http://hdl.handle.net/10271/0002000458a01d7c96-74a5-4f91-ad34-a7a7effc0803
| 名前 / ファイル | ライセンス | アクション |
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CARJ-73-639.pdf (2.8 MB)
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| Item type | 共通アイテムタイプ / Common item types(1) | |||||||||||||
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| 公開日 | 2025-06-27 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Distinction between hepatocellular carcinoma and hypervascular liver metastases in non-cirrhotic patients using gadoxetate disodium-enhanced magnetic resonance imaging | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | jpn | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | liver | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | magnetic resonance imaging | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | metastasis | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | hepatocellular carcinoma | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | Contrast agent | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ | journal article | |||||||||||||
| アクセス権 | ||||||||||||||
| アクセス権 | open access | |||||||||||||
| 著者 |
Ichikawa, Shintaro
× Ichikawa, Shintaro
× Morisaka, Hiroyuki
× Omiya, Yoshie
× Onishi, Hiroshi
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| 著者情報 |
市川, 新太郎
× 市川, 新太郎
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| 書誌情報 |
en : Canadian Association of Radiologists journal 巻 73, 号 4, p. 639-646, 発行日 2022-11 |
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| 出版者 | ||||||||||||||
| 出版者 | SAGE Publications | |||||||||||||
| 権利 | ||||||||||||||
| 権利情報 | Ichikawa S, Morisaka H, Omiya Y, Onishi H, Distinction between hepatocellular carcinoma and hypervascular liver metastases in non-cirrhotic patients using gadoxetate disodium-enhanced magnetic resonance imaging, Canadian Association of Radiologists Journal, 73(4); pp. 639-646. Copyright The Author(s) 2022. DOI: 10.1177/08465371221085516. | |||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Purpose: To identify the hallmarks of gadoxetate disodium-enhanced magnetic resonance imaging (MRI) distinguishing hepatocellular carcinoma (HCC) from hypervascular liver metastases (HLMs). Methods: Between January 2008 and October 2020, among patients who underwent gadoxetate disodium-enhanced MRI, those who met the following criteria were retrospectively included: without chronic hepatitis or liver stiffness ≤2.5 kPa on magnetic resonance elastography or F0/F1 on pathological assessment. Two blinded radiologists reviewed the imaging findings to judge the presence or absence of enhancing capsule, nonperipheral washout, corona enhancement, hypointensity in the transitional/hepatobiliary phase (HBP), hyperintensity on T2-weighted/diffusion-weighted imaging (DWI), mosaic architecture, and blood products/fat in mass. The lesion-to-liver signal intensity ratios in HBP and DWI were also calculated. Univariate and multivariate analyses were performed to identify the imaging hallmarks distinguishing HCC from HLM. Interobserver agreement was calculated using kappa values and intraclass correlation coefficients (ICCs). Results: The final study cohort comprised 72 lesions in 44 patients (mean age, 65.0±11.9 years). Univariate analysis revealed higher frequencies of the following features in HCC than in HLM (P<0.10): nonperipheral washout, corona enhancement, transitional phase hypointensity, mosaic architecture, and fat in mass (P=0.002–0.073). Multivariate analysis revealed that nonperipheral washout and mosaic architecture favored the diagnosis of HCC over that of HLM with odds ratios of 7.66 and 14.6, respectively (P=0.038 and 0.029, respectively). The interobserver agreement for each item was moderate or substantial (kappa or ICC=0.447–0.792). Conclusion: Peripheral washout and mosaic architecture may be reliable imaging hallmarks for distinguishing HCC from HLM. |
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| PISSN | ||||||||||||||
| 収録物識別子 | 0846-5371 | |||||||||||||
| EISSN | ||||||||||||||
| 収録物識別子 | 1488-2363 | |||||||||||||
| NII書誌ID (NCID) | ||||||||||||||
| 収録物識別子 | AA10801125 | |||||||||||||
| PubMed番号 (PMID) | ||||||||||||||
| 関連識別子 | 35341349 | |||||||||||||
| 出版社DOI | ||||||||||||||
| 関連識別子 | https://doi.org/10.1177/08465371221085516 | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
