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Impact of prognostic nutritional index on the occurrence of post-operative delirium after total knee arthroplasty

http://hdl.handle.net/10271/0002000729
http://hdl.handle.net/10271/0002000729
ce21841e-d0ba-4308-a6c4-962a259d0c06
名前 / ファイル ライセンス アクション
DT_ron614_ronbun.pdf 論文本文 (395 KB)
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アイテムタイプ アイテムタイプ_T/itemType_T(1)
公開日 2026-04-07
タイトル
タイトル Impact of prognostic nutritional index on the occurrence of post-operative delirium after total knee arthroplasty
言語
言語 eng
その他のタイトル
その他のタイトル 予後栄養指数が人工膝関節全置換術後のせん妄発生に与える影響
キーワード
主題 Total knee arthroplasty
キーワード
主題 Delirium
キーワード
主題 Prognostic nutritional index
キーワード
主題 Cutoff value
キーワード
主題 Malnutrition
キーワード
主題 Risk factors
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
資源タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
著者 堀田, 健介

× 堀田, 健介

ja 堀田, 健介(Personal)

ja-Kana ホッタ, ケンスケ(Personal)

en Hotta, Kensuke(Personal)

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書誌情報 en : Journal of Joint Surgery and Research

巻 2, 号 2, p. 71-76, 発行日 2024-05-18
出版者
出版者 Elsevier
出版者
出版者 日本股関節学会, 日本人工関節学会, 日本膝関節学会
権利情報
権利情報Resource https://creativecommons.org/licenses/by/4.0/
権利情報 © 2024 The Author(s). Published by Elsevier B.V. on behalf of The Japanese Hip Society, The Japanese Society for Replacement Arthroplasty and The Japanese Knee Society. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
抄録
内容記述 Purpose: Delirium has been reported to cause delayed functional recovery, prolonged hospitalization, future institutionalization, increased mortality, and increased healthcare costs. However, there are no reports on how prognostic nutritional index (PNI), Controlling Nutritional Status (CONUT) score, and geriatric nutritional risk index (GNRI) are related to delirium after total knee arthroplasty (TKA). This study aimed to identify risk factors for post-operative delirium after TKA using various pre-operative nutritional assessments (PNI, CONUT score, and GNRI).
Methods: In total, 289 patients who underwent primary TKA between September 2011 and April 2022 in our institute (Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan) were enrolled. Patients were divided into two groups: those who developed post-operative delirium (Group D), and those who did not (Group ND). Pre-operative risk factors, including nutritional indices, for post-operative delirium were evaluated.
Results: Group D comprised 16 participants, while Group ND comprised 273 participants. Comparisons between the two groups revealed significant differences in age, PNI, CONUT score, GNRI, and history of cerebrovascular disease. Multiple logistic regression analysis revealed that significant risk factors for delirium after TKA were age, PNI, and history of cerebrovascular disease. A receiver operating characteristic curve indicated that the cutoff values for delirium were 47.4 for PNI (sensitivity, 0.810; specificity, 0.875) and 78.5 years for age (sensitivity, 0.813; specificity, 0.722).
Conclusions: Risk factors for post-operative delirium after TKA were PNI<47.4, age>78.5 years, and history of cerebrovascular disease. Patients exceeding these pre-operative cutoff values or with a history of cerebrovascular disease should receive counseling about delirium before surgery.
学位名
学位名 博士(医学)
学位の区分
内容記述 doctoral
学位の分野
内容記述 医学系研究科
学位授与機関
学位授与機関名 浜松医科大学
学位授与機関名 Hamamatsu University School of Medicine
学位授与年月日
学位授与年月日 2025-04-18
学位授与番号
学位授与番号 乙第614号
EISSN
収録物識別子 2949-7051
医中誌論文ID (ICHUSHI)
関連識別子 2025236707
出版社DOI
関連識別子 https://doi.org/10.1016/j.jjoisr.2024.04.004
要旨⇔論文へのリンク
関連識別子 http://hdl.handle.net/10271/0002000414
関連名称 学位論文要旨
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
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