@article{oai:hama-med.repo.nii.ac.jp:00002349,
 author = {Suzuki, Daisuke and Nagata, Toshi and Matsumoto, Sohkichi and Matsumoto, Makoto and Tsujimura, Kunio and Koide, Yukio},
 issue = {8},
 journal = {Vaccine},
 month = {Feb},
 note = {Mycobacterial DNA-binding protein 1 (MDP1) is a major protein antigen in mycobacteria and induces protective immunity against Mycobacterium tuberculosis infection in mice. In this study we determined murine T-cell epitopes on MDP1 with MDP1 DNA immunization in mice. We analyzed interferon-γ production from the MDP1 DNA-immune splenocytes in response to 20-mer overlapping peptides covering MDP1 protein. We identified several CD4+ T-cell epitopes in three inbred mouse strains and one CD8+ T-cell epitope in C57BL/6 mice. These T-cell epitopes would be feasible for analysis of the role of MDP1-specific T-cells in protective immunity and for future vaccine design against M. tuberculosis infection.},
 pages = {2020--2025},
 title = {Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination},
 volume = {28},
 year = {2010}
}