{"created":"2023-06-20T15:47:49.159739+00:00","id":2352,"links":{},"metadata":{"_buckets":{"deposit":"bdca4ee1-649c-4835-ae76-34e9eab77129"},"_deposit":{"created_by":4,"id":"2352","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2352"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00002352","sets":["1:11"]},"author_link":[],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-11-09","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"534","bibliographicPageStart":"529","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"Int J Neuropsychopharmacol"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism. We measured concentrations of N-acetylaspartate (NAA), choline-containing compounds (Cho), and creatine plus phosphocreatine (Cr+PCr) in the hippocampal formation by proton magnetic resonance spectroscopy in 12 non-medicated male subjects with autism and 12 age- and sex-matched controls. Aggression was scored in the autistic subjects using the Buss-Perry Aggression Questionnaire. The concentrations of Cho and Cr+PCr in the hippocampal formation in autistic subjects were significantly higher than the corresponding values in control subjects, and a significant positive correlation was observed between the concentrations of these metabolites in the hippocampal formation and scores on the Buss-Perry Aggression Questionnaire in autistic subjects. Results suggest that high-functioning adult subjects with autism have abnormal metabolite concentrations in the hippocampal formation, which may in part account for their aggression.","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"CINP"}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1017/S1461145709990952","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright CINP"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"14611457","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Suzuki, Katsuaki"}]},{"creatorNames":[{"creatorName":"Nishimura, Katsuhiko"}]},{"creatorNames":[{"creatorName":"Sugihara, Genichi"}]},{"creatorNames":[{"creatorName":"Nakamura, Kazuhiko"}]},{"creatorNames":[{"creatorName":"Tsuchiya, Kenji J."}]},{"creatorNames":[{"creatorName":"Matsumoto, Kaori"}]},{"creatorNames":[{"creatorName":"Takebayashi, Kiyokazu"}]},{"creatorNames":[{"creatorName":"Isoda, Haruo"}]},{"creatorNames":[{"creatorName":"Sakahara, Harumi"}]},{"creatorNames":[{"creatorName":"Sugiyama, Toshiro"}]},{"creatorNames":[{"creatorName":"Tsujii, Masatsugu"}]},{"creatorNames":[{"creatorName":"Takei, Nori"}]},{"creatorNames":[{"creatorName":"Mori, Norio"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"IntJNP9-1.pdf","filesize":[{"value":"115.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IntJNP9-1.pdf","url":"https://hama-med.repo.nii.ac.jp/record/2352/files/IntJNP9-1.pdf"},"version_id":"67061e56-1247-4a78-a74f-49052fa7a1d4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Aggression","subitem_subject_scheme":"Other"},{"subitem_subject":"autism","subitem_subject_scheme":"Other"},{"subitem_subject":"hippocampus","subitem_subject_scheme":"Other"},{"subitem_subject":"magnetic resonance spectroscopy","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Metabolite alterations in the　hippocampus of high-functioning adult subjects with autism","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Metabolite alterations in the　hippocampus of high-functioning adult subjects with autism","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"2352","relation_version_is_last":true,"title":["Metabolite alterations in the　hippocampus of high-functioning adult subjects with autism"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T04:53:54.572708+00:00"}