@article{oai:hama-med.repo.nii.ac.jp:00002379, author = {前川, 真人 and 須藤, 加代子 and 菅野, 剛史}, issue = {1}, journal = {生物物理化学}, month = {Feb}, note = {We examined two families with silent type hypocholinesterasemia, by using electrophoretic analysis and immunological method. One case had trace amount of normal cholinesterase (ChE; EC 3.1.1.8.) activity. By immunological method, production of ChE protein was observed in the case. A part of the protein was seemed to show ChE activity. The case was suspected to be caused by a disturbance of polymerization, because C4 band was weak by electrophoretic analysis. Another case had neither ChE activity nor production of ChE protein. The former was homozygote of silent gene type II, and the latter, homozygote of silent gene type I. Therefore, heterogeneity of the silent gene is very rich in Japan and variation is demonstrated to be in some steps of ChE production.}, pages = {15--18}, title = {サイレント型コリンエステラーゼ変異の多様性}, volume = {31}, year = {1987} }