{"created":"2023-06-20T15:47:51.829283+00:00","id":2390,"links":{},"metadata":{"_buckets":{"deposit":"16281f55-cd44-4f1c-8b34-76861f6a2c5f"},"_deposit":{"created_by":4,"id":"2390","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2390"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00002390","sets":["1:11"]},"author_link":[],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1981-10-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"148","bibliographicPageStart":"141","bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"生物物理化学"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"α2-マクログロブリン(α2-M)は,分子量725,000の血漿糖蛋白である.α2-Mはほとんどいかなるendopepti・daseとも反応する.Table1にα2-Mと結合する蛋白分解酵素のスペクトラムを示す.ここに示すように非常に多くの異なった機能をもつ蛋白分解酵素がα2-Mと反応する.特に血漿の凝固,線溶,キニン系の酵素であるserine proteaseはほとんどすべてα2-Mと反応するが, 補体系のCls,Clrは反応しない. 本稿ではまずα2-Mの構造を述べ,次に血漿プロテアーゼとの反応について述べる.","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本電気泳動学会"}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2198/sbk.25.141","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本電気泳動学会"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00319082","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13499785","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高田, 明和"}]},{"creatorNames":[{"creatorName":"高田, 由美子"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"Seibutubuturi25_2-141.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Seibutubuturi25_2-141.pdf","url":"https://hama-med.repo.nii.ac.jp/record/2390/files/Seibutubuturi25_2-141.pdf"},"version_id":"08c50cfb-2084-4199-94cd-22269fdcce5d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"α2-マクログロブリンの機能について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"α2-マクログロブリンの機能について","subitem_title_language":"ja"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2011-04-16"},"publish_date":"2011-04-16","publish_status":"0","recid":"2390","relation_version_is_last":true,"title":["α2-マクログロブリンの機能について"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T05:00:41.594116+00:00"}