@article{oai:hama-med.repo.nii.ac.jp:00002414,
 author = {Katoh, Hideki and Noda, Naohisa and Hayashi, Hideharu and Satoh, Hiroshi and Terada, Hajime and Ohno, Ryuzo and Yamazaki, Noboru},
 issue = {5},
 journal = {Japanese Heart Journal},
 month = {May},
 note = {We measured intracellular Na+ concentration ([Na+]i) of diabetic rat ventricular myocytes using sodium-binding benzofuran isophthalate (SBFI). We used diabetic rats at 8 weeks after the injection of streptozotocin (45mg/kg i.v.). The level of [Na+]i during the control perfusion was significantly lower in diabetic myocytes than that in normal myocytes (9.2±0.4mM v.s. 12.0±0.3 mM, p<0.01). After the 40min perfusion of 1μM hexamethylene amiloride  (HMA), [Na+]i decreased significantly in both groups. However, there was no difference in [Na+]i between the two groups after the perfusion of HMA. It was suggested that the lower [Na+]i in diabetic myocytes could be due to the decreased activity of Na+/H+ exchange system. (Jpn Heart J 36: 647-656, 1995)},
 pages = {647--656},
 title = {Intracellular Sodium Concentration in Diabetic Rat Ventricular Myocytes},
 volume = {36},
 year = {1995}
}