{"created":"2023-06-20T15:47:55.788282+00:00","id":2444,"links":{},"metadata":{"_buckets":{"deposit":"a6e873f9-d150-4dfd-bf68-0c1a348dc40f"},"_deposit":{"created_by":4,"id":"2444","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2444"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00002444","sets":["1:11"]},"author_link":[],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"87","bibliographicPageStart":"83","bibliographicVolumeNumber":"5","bibliographic_titles":[{"bibliographic_title":"Clinical Pediatric Endocrinology"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In Turner's syndrome, the detection of Y chromosome sequences is very important because the presence of the Y chromosome increases the risk of gonadoblastoma induction. Some recent studies have indicated the presence of the Y chromosome in patients with Turner's syndrome, by methods in which the Y chromosome was not detected by a standard cytogenetic method, but these studies concentrated on a part of the Y chromosome or used an insensitive methods. In this study, we approached the detection of Y chromosome sequences by a sensitive method, polymerase chain reaction (PCR) with seven pairs of primers that span the Y chromosome, followed by Southern blot analysis, in eleven Japanese patients with Turner's syndrome. Ten of the eleven patients had some Y chromosome sequences determined by PCR followed by Southern blot. This suggests that most patients with Turner's syndrome have cryptic Y chromosomes, but further studies and long-term follow-up of patients with the Y chromosome are needed to support our data and to clarify the significance of a small amount of Y chromosome.","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本小児内分泌学会"}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1297/cpe.5.83","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"The Japanese Society for Pediatric Endocrinology"},{"subitem_rights":"本文データは学協会の許諾に基づきJournal Archiveから複製したものである"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09185739","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13477358","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nakagawa, Yuichi"}]},{"creatorNames":[{"creatorName":"Natsume, Hiromune"}]},{"creatorNames":[{"creatorName":"Kubota, Akira"}]},{"creatorNames":[{"creatorName":"Takeuchi, Hiromi"}]},{"creatorNames":[{"creatorName":"Nasuda, Kaoru"}]},{"creatorNames":[{"creatorName":"Toya, Kazuhiko"}]},{"creatorNames":[{"creatorName":"Endou, Akira"}]},{"creatorNames":[{"creatorName":"Saegusa, Hirokazu"}]},{"creatorNames":[{"creatorName":"Takeuchi, Rika"}]},{"creatorNames":[{"creatorName":"Ogawa, Haruo"}]},{"creatorNames":[{"creatorName":"Igarashi, Yoshio"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"Clinical P-5-83.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Clinical P-5-83.pdf","url":"https://hama-med.repo.nii.ac.jp/record/2444/files/Clinical P-5-83.pdf"},"version_id":"7b43d567-3652-4914-91a0-26b2a40bf821"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Turner syndrome,","subitem_subject_scheme":"Other"},{"subitem_subject":"Y chromosome,","subitem_subject_scheme":"Other"},{"subitem_subject":"PCR,","subitem_subject_scheme":"Other"},{"subitem_subject":"Southern blot","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Frequent Detection of Y Chromosome Sequences in Japanese Turner's Syndrome by Southern Blot Analysis of Amplified DNA","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Frequent Detection of Y Chromosome Sequences in Japanese Turner's Syndrome by Southern Blot Analysis of Amplified DNA","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"2444","relation_version_is_last":true,"title":["Frequent Detection of Y Chromosome Sequences in Japanese Turner's Syndrome by Southern Blot Analysis of Amplified DNA"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T05:05:23.538184+00:00"}