{"created":"2023-06-20T15:48:03.399675+00:00","id":2570,"links":{},"metadata":{"_buckets":{"deposit":"3a31c9ca-ec4e-4d3b-b481-dffa13344531"},"_deposit":{"created_by":4,"id":"2570","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2570"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00002570","sets":["1:12:55"]},"author_link":["7613","7614","7615","7616","7617","7618","7619","7620","7621"],"item_3_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Pregnancy and childbearing with nonclassic lipoid congenital adrenal hyperplasia without assisted reproductive technologies and sex hormone replacement : a case report","subitem_alternative_title_language":"en"}]},"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"43","bibliographicPageStart":"38","bibliographicVolumeNumber":"2","bibliographic_titles":[{"bibliographic_title":"静岡産科婦人科学会雑誌","bibliographic_titleLang":"ja"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"先天性副腎過形成症は、ステロイド合成酵素の欠損、コレステロールの輸送蛋白の異常により、副腎皮質過形成となる疾患で、うち、先天性リポイド副腎過形成（ lipoid  congenital adrenal hyperplasia；LCAH）は、すべてのステロイド分泌不全が生じ、最も重症型である。コレステロールをミトコンドリア内に輸送する蛋白（Steroidogenic Acute Regulatory Protein；StAR）の異常により、生後早期から副腎不全症状を呈し、性ホルモン合成も障害される。一方、女性ホルモンの分泌にはStAR非依存性の回路も存在し、生殖補助医療下の妊娠出産例が報告されている。今回我々は、LCAH非古典型患者において、性ホルモンを補充せず妊娠出産に至った症例を経験した。【症例】27歳0回経妊0回経産。13歳時、遺伝子検査にてLCAH と診断。27歳時、自然妊娠。初期より女性ホルモン分泌不全はなく、妊娠37週5日、選択的帝王切開術にて健常児を得た。【考察】LCAH 非古典型患者において、性ホルモン補充を行わず、妊娠出産管理を行いうる可能性が示唆された。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"静岡産科婦人科学会","subitem_publisher_language":"ja"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21871914","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"磯部, まり子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"市川, 義一","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"池ノ上, 学","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田, 卓博","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"根本, 泰子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"服部, 政博","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"住友, 直文","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"西澤, 和倫","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"長谷川, 奉延","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"jsog_2_1_7.pdf","filesize":[{"value":"1.1 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shift","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"progesterone","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pregnancy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"生殖補助医療、性ホルモン補充を行わず、妊娠・出産に至った先天性リポイド副腎過形成の1 例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"生殖補助医療、性ホルモン補充を行わず、妊娠・出産に至った先天性リポイド副腎過形成の1 例","subitem_title_language":"ja"}]},"item_type_id":"3","owner":"4","path":["55"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-01-05"},"publish_date":"2015-01-05","publish_status":"0","recid":"2570","relation_version_is_last":true,"title":["生殖補助医療、性ホルモン補充を行わず、妊娠・出産に至った先天性リポイド副腎過形成の1 例"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-01T06:41:19.451007+00:00"}