{"created":"2023-06-20T15:48:39.761696+00:00","id":3183,"links":{},"metadata":{"_buckets":{"deposit":"82ac9e8e-3c26-446e-89f4-a50189f19547"},"_deposit":{"created_by":4,"id":"3183","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3183"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00003183","sets":["1:12:60"]},"author_link":["9462","9463","9464","9465","9466","9467","9468"],"control_number":"3183","item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"67","bibliographicPageStart":"61","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"静岡産科婦人科学会雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of the Shizuoka Society of Obstetrics and Gynecology","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"分子標的薬であるBevacizumab (Bev) の重篤な副作用として消化管穿孔が挙げられる。今回我々は卵巣癌術後に腹腔内膿瘍を形成し、膿瘍治療後にPaclitaxel+Carboplatin (TC) +Bev療法を行い、S状結腸穿孔を発症した症例を経験したので報告する。\n症例は51歳。腹部膨満感を主訴に当科を受診した。MRI検査では両側の付属器腫瘤と大量腹水を認めた。卵巣癌の疑いで手術を施行し、術後診断は卵巣癌 (endometrioid　adenocarcinoma)、手術進行期はⅢB期 (pT3bN1M0) であった。術後に腹腔内に血腫を形成し、それが原因で腹腔内膿瘍を形成したため抗菌薬治療を施行した。術後化学療法としてTC+Bev療法を行い、維持療法としてBev単独で9コース目を投与後にS状結腸穿孔を発症した。現在はCR (complete response) となり、経過観察中である。\nBev投与の際の消化管穿孔を発症するリスク因子は、消化管の炎症と報告されている。本症例では腹腔内膿瘍治療後にBevを使用してS状結腸穿孔を発症した。慎重な症例選択を行い、合併症のリスクに注意を払う必要性を再認識させられた。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"静岡産科婦人科学会","subitem_publisher_language":"ja"}]},"item_3_relation_27":{"attribute_name":"医中誌論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2018318090","subitem_relation_type_select":"ICHUSHI"}}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"2187-1914","subitem_source_identifier_type":"EISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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Takahiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9465","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"小田, 彩子","creatorNameLang":"ja"},{"creatorName":"ODA, Ayako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9466","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"長谷川, 瑛","creatorNameLang":"ja"},{"creatorName":"HASEGAWA, Ei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9467","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 康之","creatorNameLang":"ja"},{"creatorName":"SUZUKI, Yasuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"9468","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"jsog_7_1_61.pdf","filesize":[{"value":"778.8 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併用化学療法中にS状結腸穿孔を発症した1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"卵巣癌手術後に腹腔内膿瘍を形成し Bevacizumab 併用化学療法中にS状結腸穿孔を発症した1例","subitem_title_language":"ja"},{"subitem_title":"A case of sigmoid colon perforation during chemotherapy with bevacizumab caused abscess formation after ovarian cancer surgery","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["60"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-03-23"},"publish_date":"2018-03-23","publish_status":"0","recid":"3183","relation_version_is_last":true,"title":["卵巣癌手術後に腹腔内膿瘍を形成し Bevacizumab 併用化学療法中にS状結腸穿孔を発症した1例"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2024-07-31T07:12:09.219767+00:00"}