{"created":"2023-06-20T15:48:39.761696+00:00","id":3183,"links":{},"metadata":{"_buckets":{"deposit":"e2a4271c-0512-4876-b958-b0367c480840"},"_deposit":{"created_by":4,"id":"3183","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3183"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00003183","sets":["1:12:60"]},"author_link":["9462","9463","9464","9465","9466","9467","9468"],"item_3_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"A case of sigmoid colon perforation during chemotherapy with bevacizumab caused abscess formation after ovarian cancer surgery","subitem_alternative_title_language":"en"}]},"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"67","bibliographicPageStart":"61","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"静岡産科婦人科学会雑誌","bibliographic_titleLang":"ja"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"分子標的薬であるBevacizumab(Bev)の重篤な副作用として消化管穿孔が挙げられる。今回我々は卵巣癌術後に腹腔内膿瘍を形成し、膿瘍治療後にPaclitaxel+Carboplatin(TC)+Bev療法を行い、S状結腸穿孔を発症した症例を経験したので報告する。症例は51歳。腹部膨満感を主訴に当科を受診した。MRI検査では両側の付属器腫瘤と大量腹水を認めた。卵巣癌の疑いで手術を施行し、術後診断は卵巣癌(endometrioid　adenocarcinoma)、手術進行期はⅢB期(pT3bN1M0)であった。術後に腹腔内に血腫を形成し、それが原因で腹腔内膿瘍を形成したため抗菌薬治療を施行した。術後化学療法としてTC+Bev療法を行い、維持療法としてBev単独で9コース目を投与後にS状結腸穿孔を発症した。現在はCR(complete response)となり、経過観察中である。Bev投与の際の消化管穿孔を発症するリスク因子は、消化管の炎症と報告されている。本症例では腹腔内膿瘍治療後にBevを使用してS状結腸穿孔を発症した。慎重な症例選択を行い、合併症のリスクに注意を払う必要性を再認識させられた。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"静岡産科婦人科学会","subitem_publisher_language":"ja"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21871914","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松木, 翔太郎","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"矢田, 大輔","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"東堂, 祐介","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 崇公","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小田, 彩子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"長谷川, 瑛","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 康之","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-08-27"}],"displaytype":"detail","filename":"jsog_7_1_61.pdf","filesize":[{"value":"778.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jsog_7_1_61.pdf","url":"https://hama-med.repo.nii.ac.jp/record/3183/files/jsog_7_1_61.pdf"},"version_id":"0c890e4c-4e62-463c-9b86-449984869429"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"bevacizumab","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ovarian cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intestinal perforation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"卵巣癌手術後に腹腔内膿瘍を形成しBevacizumab併用化学療法中にS状結腸穿孔を発症した1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"卵巣癌手術後に腹腔内膿瘍を形成しBevacizumab併用化学療法中にS状結腸穿孔を発症した1例","subitem_title_language":"ja"}]},"item_type_id":"3","owner":"4","path":["60"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-03-23"},"publish_date":"2018-03-23","publish_status":"0","recid":"3183","relation_version_is_last":true,"title":["卵巣癌手術後に腹腔内膿瘍を形成しBevacizumab併用化学療法中にS状結腸穿孔を発症した1例"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-01T06:54:12.053230+00:00"}