@article{oai:hama-med.repo.nii.ac.jp:00003291,
 author = {鈴木, 美沙子 and 林, 立弘 and 深田, せり乃 and 水野, 有里 and 幸村, 康弘 and 徳永, 直樹},
 issue = {2},
 journal = {静岡産科婦人科学会雑誌},
 month = {Sep},
 note = {卵巣を原発とする印環細胞癌は非常にまれといわれている。症例は44歳、0妊0産。腹囲増大と下腹部痛を主訴に受診し、径25cmの巨大な卵巣腫瘍を認めた。CEA 2496 ng/mlと高値であったが上部下部消化管の精査で異常を認めなかった。術後の病理検索でも卵巣を原発とする印環細胞癌の診断であった。術後、TC療法(パクリタキセル＋カルボプラチン)，S-1+CDDP療法(テガフール・ギメラシル・オテラシルカリウム＋シスプラチン)を行うも腹膜播腫病変が増大、水腎症・腸閉塞を発症し、術後12ヶ月で永眠された。卵巣癌の原発巣を示唆する所見としては、片側発症・大きい腫瘍径・低い進行期であることが臨床所見としては有用であり、病理所見としては良性～境界悪性～悪性の連続する組織像が認められる。ただ、卵巣原発印環細胞癌の治療方法にコンセンサスはなく、今後の報告の蓄積が望まれる。, Primary ovarian signet ring cell carcinomas are extremely rare. A 44-year-old gravida 0 para 0 female visited our hospital due to an increased abdominal circumference and lower abdominal pain, and a giant ovarian tumor (diameter, 25 cm) was identified. Although the CEA level was high (2,496 ng/mL), close examination of the upper and lower gastrointestinal tract showed no abnormality. Based on the results of postoperative pathological examination, a diagnosis of a primary ovarian signet ring cell carcinoma was made. After the operation, TC therapy (paclitaxel + carboplatin) and S-1 + CDDP therapy (tegafur, gimeracil, oteracil potassium + cisplatin) were performed, but the extent of peritoneal dissemination increased, and hydronephrosis and intestinal obstruction developed. She died 12 months after the operation. As clinical findings suggesting a primary carcinoma lesion of the ovary, unilateral development, a large tumor diameter, and a low stage are useful. As pathological findings, a histological image showing continuous benign-borderline-malignant lesions is observed. However, there is no consensus on the treatment method for primary ovarian signet ring cell carcinomas, and so the future accumulation of cases is necessary.},
 pages = {4--11},
 title = {卵巣原発印環細胞癌の一例},
 volume = {7},
 year = {2018}
}