{"created":"2023-06-20T15:48:59.389656+00:00","id":3513,"links":{},"metadata":{"_buckets":{"deposit":"340d9ce1-05b9-41d5-a061-cd6f2eac4e08"},"_deposit":{"created_by":4,"id":"3513","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3513"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00003513","sets":["1:12:72"]},"author_link":["10302","10303","10304","10305","10306","10307","10308","10309"],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"130","bibliographicPageStart":"126","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"静岡産科婦人科学会雑誌","bibliographic_titleLang":"ja"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ペグフィルグラスチムは持続性のG-CSF刺激作用を保持し、末梢血中の白血数を増加させる働きをもつ。\n症例は55歳。再発卵巣癌に対して、DC療法 (ドセタキセル70 mg/m2＋カルボプラチン AUC≓ 5) とペグフィルグラスチムを投与中であった。DC療法4コース投与後に発熱と全身倦怠感を主訴に来院した。抗菌薬投与を行ったが、解熱を認めなかった。精査目的に撮影した造影CTで胸部大動脈の壁肥厚と左側優位の両側胸水貯留を認めたため、大動脈炎と診断し、プレドニゾロンの投与を開始した。症状はただちに軽快し、大動脈の壁肥厚も改善した。\nがん化学療法時に発熱とCRPの上昇を認めた症例は、細菌感染症以外にも血管炎を考慮する必要がある。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Pegfilgrastim induces long-acting G-CSF to increase white blood cell counts in peripheral blood.\nA 55-year-old woman with recurrent ovarian cancer was treated using docetaxel plus carboplatin and pegfilgrastim. She visited our hospital due to fever and fatigue after 4 cycles of chemotherapy. Antibiotic therapy did not reduce her temperature. Contrast-enhanced computed tomography revealed a thickened thoracic aorta and bilateral pleural effusion mainly on the left side. Aortitis was diagnosed and oral prednisolone was administered. This therapy rapidly improved her symptoms and thickened thoracic aorta.\nWe must consider vasculitis caused by G-CSF in addition to bacterial infections if the patient receiving chemotherapy develops fever and increased C-reactive protein levels based on laboratory analyses.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"静岡産科婦人科学会","subitem_publisher_language":"ja"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"21871914","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松井, 克憲","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鹿野, 共暁","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"長橋, ことみ","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"大川, 直子","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"有澤, 奈良","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"成瀬, 香織","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鈴木, 留美","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"稲本, 裕","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-24"}],"displaytype":"detail","filename":"jsog_8_2_126.pdf","filesize":[{"value":"587.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"jsog_8_2_126","url":"https://hama-med.repo.nii.ac.jp/record/3513/files/jsog_8_2_126.pdf"},"version_id":"9078325b-0375-4f77-a559-c3bb9b32f0d5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"G-CSF","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pegfilgrastim","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"aortitis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"vasculitis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ペグフィルグラスチムにより大動脈炎を発症した一例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ペグフィルグラスチムにより大動脈炎を発症した一例","subitem_title_language":"ja"},{"subitem_title":"A case of aortitis following pegfilgrastim administration","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["72"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-09-24"},"publish_date":"2019-09-24","publish_status":"0","recid":"3513","relation_version_is_last":true,"title":["ペグフィルグラスチムにより大動脈炎を発症した一例"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-01T06:56:46.014963+00:00"}