{"created":"2023-06-20T15:49:04.484218+00:00","id":3617,"links":{},"metadata":{"_buckets":{"deposit":"07c86dc5-d2ee-46e9-a1f7-a96c358aca5b"},"_deposit":{"created_by":4,"id":"3617","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"3617"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00003617","sets":["1:11"]},"author_link":[],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"667","bibliographicPageStart":"662","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Gynecological endocrinology"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Gestational transient thyrotoxicosis (GTT) is associated with direct stimulation of the maternal thyroid gland by human chorionic gonadotropin (hCG). It is characterized by slightly higher thyroid hormone and lower thyroid-stimulating hormone (TSH) levels in early pregnancy and mild or no symptoms. While GTT must be distinguished from Graves’ disease (GD), which is associated with maternal and fetal complications, treated GD and new-onset GD in pregnancy are occasionally challenging to distinguish. Evaluating serum hCG levels and TSH receptor antibody (TRAb) titers can help, but the results are not irrefutable due to pregnancy-related immunosuppression. Moreover, GTT can follow unusual clinical courses in relation to some pregnancy complications. Excessive hCG production can cause severe GTT symptoms in patients with hyperemesis gravidarum, trophoblastic disease, or multiple pregnancies. Thyrotoxicosis can emerge beyond the second trimester in patients with gestational diabetes mellitus and mirror syndrome, because of delayed elevations in the hCG levels. Detailed knowledge about GTT is necessary for correct diagnoses and its appropriate management. This review focuses on the diagnosis of GTT, and, particularly, its differentiation from GD, and unusual clinical conditions associated with GTT that require comprehensive management.","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Taylor & Francis "}]},"item_3_relation_26":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"32301638","subitem_relation_type_select":"PMID"}}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1080/09513590.2020.1754391 ","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This is an Accepted Manuscript of an article published by Taylor & Francis in Gynecological Endocrinology on 17/04/2020, available online: http://www.tandfonline.com/10.1080/09513590.2020.1754391."}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0951-3590","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"1473-0766","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Iijima, Shigeo"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-04-26"}],"displaytype":"detail","filename":"Gynecol Endocrinol-36-662.pdf","filesize":[{"value":"375.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Gynecol Endocrinol-36-662.pdf","url":"https://hama-med.repo.nii.ac.jp/record/3617/files/Gynecol Endocrinol-36-662.pdf"},"version_id":"473b22ff-3179-4c9b-b2ac-3dc46e7d7af5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Gestational transient thyrotoxicosis","subitem_subject_scheme":"Other"},{"subitem_subject":"Graves' disease","subitem_subject_scheme":"Other"},{"subitem_subject":"human chorionic gonadotropin","subitem_subject_scheme":"Other"},{"subitem_subject":"pregnancy","subitem_subject_scheme":"Other"},{"subitem_subject":"thyroid-stimulating hormone receptor antibody","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Pitfalls in the assessment of gestational transient thyrotoxicosis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Pitfalls in the assessment of gestational transient thyrotoxicosis","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2021-04-26"},"publish_date":"2021-04-26","publish_status":"0","recid":"3617","relation_version_is_last":true,"title":["Pitfalls in the assessment of gestational transient thyrotoxicosis"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T05:23:35.443147+00:00"}