@article{oai:hama-med.repo.nii.ac.jp:00003822,
 author = {Tsuda, Kazumasa and Washiyama, Naoki and Takahashi, Daisuke and Shiiya, Norihiko},
 issue = {2},
 journal = {European Journal of Cardio-Thoracic Surgery},
 month = {Aug},
 note = {To prevent embolic stroke during thoracic endovascular aortic repair, we have adopted the brain isolation technique since June 2014 in nine selected high risk patients (9/134: 6.7%) having ulcerated or protruding atheromas within the proximal aorta. Cardiopulmonary bypass was used to prevent aortic atheromas from entering the brain. We used a heparin-coated closed-loop cardiopulmonary bypass system incorporating a soft reservoir bag with 1 mg/kg heparin to minimize the disadvantages of extracorporeal circulation. The bypass graft (right axillary-left carotid-left axillary) was used as an arterial inflow in patients undergoing zone-1 landing (n=8), while peripheral cannulation into three brachiocephalic arteries was employed in the remaining patient. Initial pump flow was set at 1.3 L/min/m2, and native cardiac output was reduced by adjusting the reservoir bag volume. Aortography was performed to confirm non-visualization of the arch vessels before catheter manipulation. There was no mortality and one solitary left cerebellar infarction.},
 pages = {420--422},
 title = {Functional brain isolation technique for stroke prevention in thoracic endovascular aortic repair},
 volume = {60},
 year = {2021}
}