{"created":"2023-06-20T15:49:26.536217+00:00","id":4033,"links":{},"metadata":{"_buckets":{"deposit":"ccdd0162-bec1-44f8-98d2-ed76e13a1a89"},"_deposit":{"created_by":4,"id":"4033","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"4033"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00004033","sets":["1:11"]},"author_link":["12468","12469","12470","12471","12472","12473","12474","12475","12476","12477"],"item_3_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Chemoradiotherapy versus esophagectomy for early esophageal cancer"}]},"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"1844","bibliographicPageStart":"1835","bibliographicVolumeNumber":"45","bibliographic_titles":[{"bibliographic_title":"World Journal of Surgery"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: The standard treatment for patients with clinical T1bN0M0 esophageal squamous cell carcinoma is radical esophagectomy. Definitive chemoradiotherapy is regarded as a treatment option, and recently, good clinical outcomes of this treatment have been reported. This study compared prognosis after definitive chemoradiotherapy with radical esophagectomy.\nMethods: From January 2011 to December 2019, 68 consecutive patients who were diagnosed clinical T1bN0M0 squamous cell carcinoma were enrolled and investigated retrospectively. Patients were classified into two groups whether treated by surgery or definitive chemoradiotherapy. Survival outcomes were compared and subsequent therapies after recurrence were also investigated.\nResults: Among 68 patients, 39 patients underwent surgery and 29 patients received definitive chemoradiotherapy. No significant difference was noted in overall survival between the two groups. However, the rate of 5-year recurrence free survival was significantly lower in definitive chemoradiotherapy group than that of surgery group (91.1% vs. 62.7%, Hazard ratio 3.976, 95% Confidence interval 1.076?14.696, p=0.039). Patients who had local recurrence after definitive chemoradiotherapy received endoscopic submucosal dissection or photodynamic therapy as salvage therapies, and resulted in no disease progression and a good prognosis.\nConclusions: Definitive chemoradiotherapy may become a promising alternative therapy comparable with radical esophagectomy in patients with clinical T1bN0M0 esophageal squamous cell carcinoma. Early detection of recurrence by frequent follow-up after definitive chemoradiotherapy is important to control disease within local recurrence, and salvage therapy for local lesions could contribute to long term survival.","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature "}]},"item_3_relation_26":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"33620541","subitem_relation_type_select":"PMID"}}]},"item_3_relation_28":{"attribute_name":"出版社DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1007/s00268-021-06016-4","subitem_relation_type_select":"DOI"}}]},"item_3_rights_7":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00268-021-06016-4"}]},"item_3_source_id_19":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0364-2313","subitem_source_identifier_type":"ISSN"}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"1432-2323","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Haneda, Ryoma"}],"nameIdentifiers":[{"nameIdentifier":"12468","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Booka, Eisuke"}],"nameIdentifiers":[{"nameIdentifier":"12469","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ishii, Kenjiro"}],"nameIdentifiers":[{"nameIdentifier":"12470","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kikuchi, Hirotoshi"}],"nameIdentifiers":[{"nameIdentifier":"12471","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hiramatsu, Yoshihiro"}],"nameIdentifiers":[{"nameIdentifier":"12472","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kamiya, Kinji"}],"nameIdentifiers":[{"nameIdentifier":"12473","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ogawa, Hirofumi"}],"nameIdentifiers":[{"nameIdentifier":"12474","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yasui, Hirofumi"}],"nameIdentifiers":[{"nameIdentifier":"12475","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takeuchi, Hiroya"}],"nameIdentifiers":[{"nameIdentifier":"12476","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsubosa, Yasuhiro"}],"nameIdentifiers":[{"nameIdentifier":"12477","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-06-10"}],"displaytype":"detail","filename":"WJS-45-1835.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"WJS-45-1835.pdf","url":"https://hama-med.repo.nii.ac.jp/record/4033/files/WJS-45-1835.pdf"},"version_id":"a61966e5-4297-4aaf-aa11-8c9f6555270b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"esophageal squamous cell carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"esophagectomy","subitem_subject_scheme":"Other"},{"subitem_subject":"chemoradiotherapy","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evaluation of definitive chemoradiotherapy versus radical esophagectomy in clinical T1bN0M0 esophageal squamous cell carcinoma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of definitive chemoradiotherapy versus radical esophagectomy in clinical T1bN0M0 esophageal squamous cell carcinoma","subitem_title_language":"en"}]},"item_type_id":"3","owner":"4","path":["11"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-06-10"},"publish_date":"2022-06-10","publish_status":"0","recid":"4033","relation_version_is_last":true,"title":["Evaluation of definitive chemoradiotherapy versus radical esophagectomy in clinical T1bN0M0 esophageal squamous cell carcinoma"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-08-02T07:16:34.645892+00:00"}