@article{oai:hama-med.repo.nii.ac.jp:00004040, author = {杉本, 健 and 花井, 洋行}, issue = {3}, journal = {日本臨牀 = Japanese Journal of Clinical Medicine}, month = {Mar}, note = {通巻第1210号, In the intestinal mucosa of inflammatory bowel disease, leukocytes are excessively activated, affecting the progress and persistence of inflammation. Cytapheresis is a treatment method that improves intestinal inflammation in patients with inflammatory bowel disease by removing these activated leukocytes from the blood. It is a safe treatment method with fewer side effects than other drug therapies involving steroids and immunosuppressants; recently, it was speculated that cytapheresis might have a previously unknown effect in improving the diminished effect of biologics such as infliximab. In the future, it is necessary to formulate more effective treatment regimens and their positioning in treatment algorithms based on evidence.}, pages = {465--469}, title = {血球成分除去療法}, volume = {80}, year = {2022} }