{"created":"2023-06-20T15:49:34.795860+00:00","id":4160,"links":{},"metadata":{"_buckets":{"deposit":"96430690-8550-42ed-9edd-7149ba29d32e"},"_deposit":{"created_by":4,"id":"4160","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"4160"},"status":"published"},"_oai":{"id":"oai:hama-med.repo.nii.ac.jp:00004160","sets":["1:75:95"]},"author_link":["12919","12920","12921","12922","12923","12924","12925","12926"],"item_3_biblio_info_5":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"52","bibliographicPageStart":"45","bibliographicVolumeNumber":"3","bibliographic_titles":[{"bibliographic_title":"浜松医科大学小児科学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Hamamatsu Journal of Pediatrics","bibliographic_titleLang":"en"}]}]},"item_3_description_9":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"抗血管内皮増殖因子（vascular endothelial growth factor : VEGF）療法は，未熟児網膜症（retinopathy of prematurity : ROP）に対する新しい治療法であり，2019年にラニビズマブが抗VEGF薬として初めてROPに対しての適応が承認された．それをうけて当院でもこれまで抗VEGF療法を5例に施行した．\n5例とも従来の光凝固療法に比べて短時間で治療が完了し，治療後1週間で病期の改善が得られた．症例1はその後全身状態が増悪しフォローができなかった．症例2,3,4はフォローアップ中に再燃し，症例2は追加の抗VEGF療法を行ったのち光凝固療法も追加した．症例3,4はフォローアップ中に無治療で病勢が改善した．症例5は再燃はなかったものの，正常な網膜血管の伸展が悪かった．\nROPのフォローアップは，治療の時期を逃さないため基本的に1週間毎に行い，徐々に間隔を延ばしていく．抗VEGF療法は光凝固療法に比べ再燃のリスクが高いため，治療後の1週間毎のフォローアップ期間が長く，退院時期の検討にROPの病勢を考慮に入れる必要がある．","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_3_publisher_6":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"浜松医科大学小児科学雑誌編集部","subitem_publisher_language":"ja"}]},"item_3_relation_27":{"attribute_name":"医中誌論文ID","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"2024010990","subitem_relation_type_select":"ICHUSHI"}}]},"item_3_source_id_20":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"2436-2433","subitem_source_identifier_type":"EISSN"}]},"item_3_version_type_32":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open 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智香","creatorNameLang":"ja"},{"creatorName":"FUJITA, Tomoka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12923","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"古森, 美和","creatorNameLang":"ja"},{"creatorName":"KOMORI, Miwa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12924","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"彦谷, 明子","creatorNameLang":"ja"},{"creatorName":"HIKOYA, Akiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12925","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"飯嶋, 重雄","creatorNameLang":"ja"},{"creatorName":"IIJIMA, Shigeo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"12926","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-03-15"}],"displaytype":"detail","filename":"hjop_3_1_45.pdf","filesize":[{"value":"881.9 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