| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
HPLC/MS/MSによるパラコートおよびジクワットの分析 |
|
言語 |
ja |
| 言語 |
|
|
言語 |
jpn |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| その他のタイトル |
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|
その他のタイトル |
Determination of paraquat and diquat by HPLC/MS/MS |
| 著者 |
李, 暁鵬
熊澤, 武志
近藤, 圭
佐藤, 啓造
石井, 晃
妹尾, 洋
鈴木, 修
|
| 書誌情報 |
ja : 法中毒
en : Japanese journal of forensic toxicology
巻 19,
号 2,
p. 174-175,
発行日 2001-05-15
|
| 出版者 |
|
|
出版者 |
日本法中毒学会 |
|
言語 |
ja |
| 権利 |
|
|
権利情報 |
Copyright 日本法中毒学会 |
| 権利 |
|
|
権利情報 |
本文データは日本法中毒学会の許諾のもと掲載しています。 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Paraquat and diquat contained in human whole blood and urine samples have been analyzed by high-performance liquid chromatography (HPLC)/tandem mass spectrometry (MS/MS) with positive ion electrospray ionization. Paraquat, diquat and ethyl paraquat as internal standard (IS) formed base peaks due to [M-H]+ ions by HPLCIMS. By use of HPLC/MS/MS, the product ions produced from each quasi-molecular ion showed the base peaks at m/z 169 for paraquat, m/z 157 for diquat and m/z 185 for IS. Selected reaction monitoring (SRM) and selected ion monitoring (SIM) were compared for the detection of the compounds from whole blood and urine. SRM showed much higher sensitivity than SIM for both types of sample. Therefore, recovery rates, regression equations and detection limits were studied for paraquat and diquat by SRM with HPLC/MS/MS. The recoveries of paraquat and diquat extracted from whole blood were 57-79 %; those from urine were 91-94 %. The regression equations for paraquat and diquat showed excellent linearity in the range of 0.5-10 ng on column with the detection limits of 0.25 ng on column for whole blood and 0.1 ng on column for urine. |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
09159606 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
FT-19-174.pdf (121.6 kB)
