| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
MAGNESIUM RESTRICTION AFFECTS TOXICITY OF PARAQUAT AND TISSUE COPPER AND IRON IN PARAQUAT-DOSED RATS |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Paraquat |
| キーワード |
|
|
主題 |
Magnesium |
| キーワード |
|
|
主題 |
Copper |
| キーワード |
|
|
主題 |
Iron |
| キーワード |
|
|
主題 |
Mineral restriction |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| その他のタイトル |
|
|
その他のタイトル |
パラコート摂取ラットにおける組織中CuとFeの濃度に及ぼすMg減食の効果 |
| 著者 |
Minakata, Kayoko
Nozawa, Hideki
Watanabe, Kanako
Suzuki, Osamu
Saito, Shin-ichi
Suzuki, Kanako
|
| 書誌情報 |
ja : 法中毒
en : Japanese journal of forensic toxicology
巻 19,
号 3,
p. 251-256,
発行日 2001-09-15
|
| 出版者 |
|
|
出版者 |
日本法中毒学会 |
|
言語 |
ja |
| 権利 |
|
|
権利情報 |
Copyright 日本法中毒学会 |
| 権利 |
|
|
権利情報 |
本文データは日本法中毒学会の許諾のもと掲載しています。 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
It seems very useful to find out nutrients including metals effective for chronic paraquat (PQ) toxicity, because pollution of the herbicide is one of the worldwide problems. The present work deals with the effects of Mg restriction on tissue Cu and Fe levels and on PQ toxicity in PQ-dosed rats. Wistar-ODS rats were fed with either Mg restricted diet containing PQ or mineral adequate diet containing PQ. The concentration of PQ in the diet was 125 ppm not to cause PQ toxicosis at least for 14 days in the rats with the adequate diet. The mineral adequate diet was based on the American Institute of Nutrition-76, and in the Mg restricted diet, the concentration of Mg was a half of that in the adequate diet. The rats fed with the Mg restricted diet began to display the symptoms of PQ toxicosis from day 4; the Mg-restricted and control rats were sacrificed on day 8. In the restricted rats, Cu concentrations increased about 2-fold in the liver and 1.5-fold in the lung and plasma, but decreased 0.6-fold in the kidney; Fe concentrations increased 1.8-fold in the liver, but decreased 0.7-fold in plasma. The restriction of Mg in the diet did not cause decrease in tissue Mg levels, but caused 1.3-fold increase in the Mg levels in the kidney and 1.2-fold increase in the spleen and plasma. |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
09159606 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
FT-19-251.pdf (348.3 kB)
