| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
Simple and selective determination of arsenite and arsenate by electrospray ionization mass spectrometry |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Arsenite |
| キーワード |
|
|
主題 |
Arsenate |
| キーワード |
|
|
主題 |
Mass spectrometry |
| キーワード |
|
|
主題 |
Electrospray ionization |
| キーワード |
|
|
主題 |
Pyrrolidinedithiocarbamate |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Minakata, Kayoko
Suzuki, Masako
Suzuki, Osamu
|
| 書誌情報 |
en : Analytica Chimica Acta
巻 631,
号 1,
p. 87-90,
発行日 2009-01-05
|
| 出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
| 権利 |
|
|
権利情報 |
Copyright 2008 Elsevier B.V. |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Arsenic pollution of public water supplies has been reported in various regions of the world. Recently, some cancer patients are treated with arsenite (AsIII); most Japanese people consume seafoods containing large amounts of negligibly toxic arsenic compounds. Some of these arsenic species are metabolized, but some remain intact. For the determination of toxic AsIII, a simple, rapid and sensitive method has been developed using electrospray ionization mass spectrometry (ESI-MS). AsIII was reacted with a chelating agent, pyrrolidinedithiocarbamate (PDC, C4H8NCSS-) and tripyrrolidinedithiocarbamate-arsine, As(PDC)3, extracted with methyl isobutyl ketone (MIBK). A 1-μL aliquot of MIBK layer was directly injected into ESI-MS instrument without chromatographic separation, and was detected within 1 min. Arsenate (AsV) was reduced to AsIII with thiosulfate, and then the total inorganic As was quantified as AsIII. This method was validated for the analysis of urine samples. The limit of detection of As was 0.22μgL-1 using 10μL of sample solution, and it is far below the permissible limit of As in drinking water, 10μgL-1, recommended by the WHO. Results were obtained in <10 min with a linear calibration range of 1-100μgL-1. Several organic arsenic compounds in urine did not interfere with AsIII detection, and the inorganic As in the reference materials SRM 2670a and 1643e were quantified after the reduction of AsV to AsIII. |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00032670 |
| 出版社DOI |
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|
関連タイプ |
isVersionOf |
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1016/j.aca.2008.10.016 |
| 著者版フラグ |
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|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
ACA-631-87.pdf (243.3 kB)
