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ゲッ歯類を用いた長期安全性試験から得られる定量データの取り扱い ―多群間で不等分散を示した一事例 ―
http://hdl.handle.net/10271/209
http://hdl.handle.net/10271/209cf3114ff-7d20-4e1a-88bb-1e1882286595
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
kiyo07_07.pdf (291.5 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||
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| 公開日 | 2013-08-27 | |||||||
| タイトル | ||||||||
| タイトル | ゲッ歯類を用いた長期安全性試験から得られる定量データの取り扱い ―多群間で不等分散を示した一事例 ― | |||||||
| 言語 | ja | |||||||
| タイトル | ||||||||
| タイトル | Statistical Processing Methods for Quantitative Data from Long Term Rodent Bioassays ―A Case Shown Heterogeneous in Variance among the Groups― | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | jpn | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Statistical analysis | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Outlier value | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Rejection test | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Rodent toxicity study | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Heterogeneous in variance | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | departmental bulletin paper | |||||||
| アクセス権 | ||||||||
| アクセス権 | open access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
| 著者 |
小林, 克己
× 小林, 克己
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| 書誌情報 |
ja : 浜松医科大学紀要. 一般教育 en : Reports of Liberal Arts, Hamamatsu University School of Medicine 号 7, p. 105-111, 発行日 1993-03-31 |
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| 出版者 | ||||||||
| 出版者 | 浜松医科大学 | |||||||
| 言語 | ja | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | The statistical analysis methods of quantitative data in long term rodent bioassay, t-tests and an analysis of variance (ANOVA) including a nonparametric analysis are commonly used by the decision tree for selecting hypothesis-testing procedures. However, occasionally, no significant differences by t-tests and nonparametric data analyzed by Barrtlett's test for homogeneity of variance are observed due to the outlier (abnormal) values in some groups. Those data are analyzed as the nonparametric values in case of heterogeneity in variance, and the significant differences are occasionally observed between control and treated groups, in spite of showing the same mean values in the 2 groups. Consequently, it is difficult to judge the influence of test substance on them. As the improvement methods for examining, the heterogeneous data in variance by a decision tree, outlier value which chosen by macroscopic finding is recommended to analyze by the Thompson's rejection test. And if the significant difference is observed this value will be excluded from the group as the outlier value. Those homogeneous data must be analyzed by the Student' t-test or ANOVA. An example was given to illustrate these sources of variability. | |||||||
| 言語 | en | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 0914-0174 | |||||||
| NII書誌ID | ||||||||
| 収録物識別子タイプ | NCID | |||||||
| 収録物識別子 | AN10032827 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
