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Stomach, liver, kidney and skeletal muscle autoregulation evaluated by near-infrared spectroscopy in a swine model
http://hdl.handle.net/10271/0002000068
http://hdl.handle.net/10271/00020000687a46ed50-30a0-4edf-9328-24d11207b910
| 名前 / ファイル | ライセンス | アクション |
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JCMC-37-899.pdf (1089 KB)
Restricted Access
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| 公開日 | 2024-02-13 | |||||||||||||
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| タイトル | Stomach, liver, kidney and skeletal muscle autoregulation evaluated by near-infrared spectroscopy in a swine model | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | Autoregulation | |||||||||||||
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| 主題 | near-infrared spectroscopy | |||||||||||||
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| 主題 | skeletal muscle | |||||||||||||
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| 主題 | splanchnic organs | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| アクセス権 | ||||||||||||||
| アクセス権 | open access | |||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||
| 著者 |
Kurita, Tadayoshi
× Kurita, Tadayoshi
× Kawashima, Shingo
× Ibrahim Khaleelullah, Mohamed Mathar Sahib
× Nakajima, Yoshiki
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| 書誌情報 |
en : Journal of Clinical Monitoring and Computing 巻 37, 号 3, p. 899-909, 発行日 2023-06 |
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| 出版者 | ||||||||||||||
| 出版者 | Springer Nature | |||||||||||||
| 言語 | en | |||||||||||||
| 権利 | ||||||||||||||
| 権利情報 | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s10877-022-00956-5 | |||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Purpose: Different organs have different autoregulatory capacities for blood pressure changes and/or circulatory volume changes. This study assessed the autoregulation of the stomach, liver, kidney and skeletal muscle, under baseline, hypovolemic, and post-fluid-resuscitation conditions using near-infrared spectroscopy (NIRS). Methods: Ten pigs (bodyweight 24.5 ± 0.5kg) were anesthetized with 2.5% isoflurane and administered 0.5, 1, 2 and 5μg kg-1 min-1 of phenylephrine at 10-min intervals, followed by similar stepwise infusion of sodium nitroprusside (SNP) to induce a wide range of mean arterial pressures (MAPs). A 600-ml bleed was induced to create the hypovolemic condition, and only phenylephrine was re-administered. Hydroxyethyl starch (600ml) was infused to create the post-fluid-resuscitation condition, and phenylephrine and SNP were re-administered. Average relationships between mean arterial pressure (MAP) and each tissue oxygenation index (TOI) were assessed, and the individual relationships were evaluated based on the correlation coefficients between MAP and TOI during each vasoactive drug infusion. Results: Based on the evaluation using each TOI as a substitute of blood flow, the kidney autoregulation was robust, similar to muscle, but had a prominent lower limit. The stomach had weaker autoregulation than the kidney and muscle. The liver had no autoregulation. The kidney TOI showed 2-fold greater changes in response to volume condition changes than the stomach and liver TOIs. Conclusions: In our NIRS-based assessment of autoregulatory capacity, the liver oxygenation is highly blood pressure dependent, and the kidney is highly susceptible and the skeletal muscle is highly tolerable to low blood pressure and volume loss. |
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| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 1387-1307 | |||||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 1573-2614 | |||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA11203617 | |||||||||||||
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| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | PMID | |||||||||||||
| 関連識別子 | 36596969 | |||||||||||||
| 出版社DOI | ||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.1007/s10877-022-00956-5 | |||||||||||||
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| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
