| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
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|
タイトル |
Vasodilator Stress Impairs the Left Ventricular Function Obtained With Gated Single-Photon Emission Computed Tomography in Patients With Known or Suspected Coronary Artery Disease |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Adenosine |
| キーワード |
|
|
主題 |
Exercise |
| キーワード |
|
|
主題 |
Ischemia |
| キーワード |
|
|
主題 |
Left ventricular function |
| キーワード |
|
|
主題 |
Single-photon emission computed tomography (SPECT) |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Odagiri, Keiichi
Uehara, Akihiko
Kurata, Chinori
|
| 書誌情報 |
Circulation Journal
巻 74,
号 12,
p. 2666-2673,
発行日 2010-12
|
| 出版者 |
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出版者 |
THE JAPANESE CIRCULATION SOCIETY |
| 権利 |
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|
権利情報 |
Copyright 2010 THE JAPANESE CIRCULATION SOCIETY |
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Transient ischemic dilatation (TID) and post-stress dysfunction of the left ventricle (LV) are important markers of severe coronary artery disease (CAD). To clarify the effects of stressor type on TID and post-stress LV dysfunction, changes in LV measurements were compared between patients with exercise- or vasodilator-induced stress. Methods and Results: The 689 patients referred for technetium-99m tetrofosmin myocardial perfusion imaging were included. Patients were stressed with either a vasodilator (n=236) or exercise (n=453). LV measurements were obtained with ECG-gated SPECT. LV end-diastolic and end-systolic volume indexes (LVEDVI, LVESVI) increased and LV ejection fraction (LVEF) decreased after stress in the vasodilator-stress group. Vasodilator-stress and the summed difference score (SDS) were independent variables that decreased LVEF after stress. Even in patients without reversible defects, vasodilator-stress impaired LV function. There were no differences in the stress-to-rest ratios of LVEDVI (rEDV) and LVESVI (rESV) among patients with normal myocardial perfusion, fixed defects and reversible defects in the vasodilator-stress group, whereas in the exercise-stress group, rESV was significantly higher in the patients with reversible defects than in those without reversible defects. Within the vasodilator-stress group, neither rEDV nor rESV correlated with the SDS. Conclusions: Vasodilator-stress by itself decreases LVEF after stress. TID should be carefully interpreted when vasodilator-stress is used to detect severe CAD. |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
13469843 |
| EISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
13474820 |
| 出版社DOI |
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関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1253/circj.CJ-10-0299 |
| 著者版フラグ |
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
CircJ74_12-2666.pdf (615.5 kB)
