Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2013-08-27 |
タイトル |
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タイトル |
Effects of L-Carnitine on Exercise Tolerance in Patients with Stable Angina Pectoris |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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主題 |
L-Carnitine |
キーワード |
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主題 |
Angina pectoris |
キーワード |
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主題 |
Exercise test |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
著者 |
Kamikawa, Tadashi
Suzuki, Yoshikazu
Kobayashi, Akira
Hayashi, Hideharu
Masumura, Yoshinori
Nishihara, Kenji
Abe, Masaaki
Yamazaki, Noboru
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書誌情報 |
Japanese Heart Journal
巻 25,
号 4,
p. 587-597,
発行日 1983-07-25
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出版者 |
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出版者 |
International Heart Journal Association |
権利 |
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権利情報 |
by International Heart Journal Association |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
The effects of L-carnitine (900mg, p.o. daily) on exercise performance were studied in 12 patients with stable effort angina using a multistage treadmill exercise test. Exercise tests were performed at the end of the placebo period and after 4 and 12 weeks of carnitine therapy. While 12 patients experienced angina during treadmill tests in the placebo period, 2 patients were free of angina after treatment with carnitine. The mean exercise time was 11.4±0.7min (mean±SE) in the placebo period. This increased significantly to 12.2±0.5min (p<0.05) after 4 weeks and 12.8±0.5min (p<0.01) after 12 weeks of treatment with carnitine. The time required for 1mm ST depression to occur was 6.4±0.9min in the placebo period. This increased significantly to 7.6±0.9min (p<0.01) after 4 weeks and 8.8±1.0min after 12 weeks of treatment with carnitine. There was significantly less ST segment depression during the same exercise load after 12 weeks of treatment as compared with that in the placebo period (p<0.05). The heart rate and the pressure rate product at the same work load showed no significant difference among the 3 testing periods. The results of this study suggest that L-carnitine may improve exercise tolerance in patients with effort angina. |
ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
00214868 |
EISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1348673X |
出版社DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.1536/ihj.25.587 |
著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |