Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2013-08-27 |
タイトル |
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タイトル |
Electrical Heterogeneity and Conduction Block in Reoxygenated Guinea Pig Papillary Muscles |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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主題 |
Delayed afterdepolarization |
キーワード |
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主題 |
Triggered activity |
キーワード |
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主題 |
Action potential duration |
キーワード |
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主題 |
Calcium |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
著者 |
Hayashi, Hideharu
Terada, Hajime
Terence, F. Mcdonald
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書誌情報 |
Japanese Heart Journal
巻 37,
号 3,
p. 383-391,
発行日 1995-11-01
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出版者 |
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出版者 |
International Heart Journal Association |
権利 |
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権利情報 |
by International Heart Journal Association |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
To investigate the changes in electrical activity after reoxygenation, guinea pig papillary muscles were reoxygenated with 5mM glucose solution after various durations (30-120min) of substrate-free hypoxia. Action potential duration recovered to the control level on reoxygenation following 30-120min hypoxia. The recovery of developed tension or resting tension was incomplete after reoxygenation following longer periods of hypoxia. There was a high incidence of arrhythmias on reoxygenation after 60min hypoxia, which have been shown to be triggered activities due to delayed afterdepolarizations. In some muscles reoxygenated after prolonged hypoxia (90-120min), there was electrical heterogeneity which was shown by variable action potential durations and configurations. There was also conduction block around the microelectrode site in muscle. It was suggested that the electrical heterogeneity and conduction block could predispose to reentry, and that triggered activities and reentry could be involved in the genesis of arrhythmias on reperfusion. (Jpn Heart J 1996; 37: 383-391) |
ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
00214868 |
EISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1348673X |
出版社DOI |
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関連タイプ |
isIdenticalTo |
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識別子タイプ |
DOI |
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関連識別子 |
10.1536/ihj.37.383 |
著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |