| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
Determination of platinum derived from cisplatin in human tissues using electrospray ionization mass spectrometry |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Platinum |
| キーワード |
|
|
主題 |
Electrospray ionization |
| キーワード |
|
|
主題 |
Mass spectrometry |
| キーワード |
|
|
主題 |
Diethyldithiocarbamate |
| キーワード |
|
|
主題 |
Silver |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Minakata, Kayoko
Nozawa, Hideki
Okamoto, Naoko
Suzuki, Osamu
|
| 書誌情報 |
en : Journal of Chromatography B
巻 832,
号 2,
p. 286-291,
発行日 2006-03-07
|
| 出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
| 権利 |
|
|
権利情報 |
(C) Elsevier |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Determination of platinum (Pt) derived from cisplatin in tissues was performed by electrospray ionization mass spectrometry (ESI-MS) using silver (Ag) as the internal standard. Pt and Ag reacted with diethyldithiocarbamate (DDC), and were extracted using isoamylalcohol and acidified with oxalic acid. The compounds were termed Pt(DDC)3 + and Ag(DDC)2 +, based on their m/z values exhibiting the highest peaks at m/z 639 and m/z 405, respectively. The limit of detection was 30 pg and the quantitation range was from 100 to 10000 pg using 5 mg tissue. The present method allowed the determination of Pt in wet-ashed tissue in 10 minutes. |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
1570-0232 |
| EISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1873-376X |
| PubMed番号 |
|
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
16483858 |
| 出版社DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1016/j.jchromb.2006.01.016 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
JCB-832-286.pdf (448.3 kB)
