Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2013-08-27 |
タイトル |
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タイトル |
BMP4 expression in the adult rat brain |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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主題 |
dendrite |
キーワード |
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主題 |
neuropil |
キーワード |
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主題 |
immunohistochemistry |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
著者 |
Mikawa, Sumiko
Wang, Cong
Sato, Kohji
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書誌情報 |
en : Journal of Comparative Neurology
巻 499,
号 4,
p. 613-625,
発行日 2006-10-06
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出版者 |
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出版者 |
Wiley InterScience |
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言語 |
en |
抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
Bone morphogenetic protein-4 (BMP4) is a member of the transforming growth factor β (TGF- β) superfamily and plays important roles in multiple biological events. Although BMP4 expression has been well described in the early development of central nervous system (CNS), little information is available for its expression in the adult CNS. We, thus, investigated BMP4 expression in the adult rat CNS using immunohistochemistry. BMP4 is intensely expressed in most neurons and their dendrites. In addition, intense BMP4 expression was also observed in the neuropil of the gray matters where high plasticity is reported, such as the molecular layer of the cerebellum and the superficial layer of the superior colliculus. Furthermore, we found that astrocytes also express BMP4 protein. These data indicate that BMP4 is more widely expressed throughout the adult CNS than previously reported, and its continued abundant expression in the adult brain strongly supports the idea that BMP4 plays pivotal roles also in the adult brain. |
注記 |
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内容記述 |
雑誌掲載タイトル:Bone morphogenetic protein-4 expression in the adult rat brain |
ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0021-9967 |
EISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1096-9861 |
PubMed番号 |
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関連タイプ |
isVersionOf |
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識別子タイプ |
PMID |
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関連識別子 |
17029256 |
出版社DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1002/cne.21125 |
著者版フラグ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |