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Evaluating mucosal healing using colon capsule endoscopy predicts outcome in patients with ulcerative colitis in clinical remission
http://hdl.handle.net/10271/00003717
http://hdl.handle.net/10271/00003717005f4b79-c7bb-442a-86e9-c86b52e8ee8f
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
論文本文 (1.2 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||
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| 公開日 | 2020-04-28 | |||||||
| タイトル | ||||||||
| タイトル | Evaluating mucosal healing using colon capsule endoscopy predicts outcome in patients with ulcerative colitis in clinical remission | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題 | Colon capsule endoscopy | |||||||
| キーワード | ||||||||
| 主題 | Ulcerative colitis | |||||||
| キーワード | ||||||||
| 主題 | Mucosal healing | |||||||
| キーワード | ||||||||
| 主題 | Mayo endoscopic subscore | |||||||
| キーワード | ||||||||
| 主題 | Ulcerative Colitis Endoscopic Index of Severity | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||
| 資源タイプ | doctoral thesis | |||||||
| アクセス権 | ||||||||
| アクセス権 | open access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
| その他のタイトル | ||||||||
| その他のタイトル | 大腸カプセル内視鏡を用いた粘膜治癒評価は臨床的寛解期潰瘍性大腸炎患者の再燃を予測する | |||||||
| 著者 |
高野, 亮佑
× 高野, 亮佑
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| 書誌情報 |
en : World journal of clinical cases 巻 6, 号 15, p. 952-960, 発行日 2018-12-06 |
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| 出版者 | ||||||||
| 出版者 | Baishideng Publishing Group | |||||||
| 言語 | en | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | AIM To examine whether second generation of colon capsule endoscopy (CCE-2) is acceptable for assessing the severity of mucosal inflammation and evaluating mucosal healing using CCE-2 is able to predict outcome in ulcerative colitis (UC) patients, especially in clinical remission. METHODS A total of 30 consecutive UC patients in clinical remission were enrolled to undergo CCE-2. Clinical remission was defined as clinical activity index (CAI) ?4 according to Rachmilewitz index. The rate of total colon observation and colon cleansing level were evaluated. Severity of mucosal inflammation in UC was assessed according to the Mayo endoscopic subscore (MES) and Ulcerative Colitis Endoscopic Index of Severity (UCEIS). Relapse-free survival was assessed. Acceptability of CCE-2 was assessed using a questionnaire survey. RESULTS The rate of total colon observation within its battery life was 93.3%. The proportion of “excellent” plus “good” cleansing level was 73.3%. The rate of mucosal healing (MES 0,1) assessed by CCE-2 was 77.0%. The relapse-free survival rate was significantly higher in MES 0,1 than in MES 2,3 (P=0.0435), and in UCEIS 0-3 than in UCEIS 4-8 (P=0.0211), whereas there was no significant difference between CAI 0 and CAI 1-4 groups. A questionnaire survey revealed an overall acceptability of CCE. CONCLUSION CCE-2 is acceptable for assessing the severity of mucosal inflammation in UC patients, especially in clinical remission. Evaluating mucosal healing using CCE-2 was able to predict outcome. |
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| 言語 | en | |||||||
| 学位名 | ||||||||
| 学位名 | 博士（医学） | |||||||
| 学位の区分 | ||||||||
| 内容記述 | doctoral | |||||||
| 学位の分野 | ||||||||
| 内容記述 | 医学系研究科 | |||||||
| 学位授与機関 | ||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||
| 学位授与機関識別子 | 13802 | |||||||
| 学位授与機関名 | 浜松医科大学 | |||||||
| 学位授与年月日 | ||||||||
| 学位授与年月日 | 2019-12-13 | |||||||
| 学位授与番号 | ||||||||
| 学位授与番号 | 甲第820号 | |||||||
| EISSN | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 2307-8960 | |||||||
| PubMed番号 | ||||||||
| 識別子タイプ | PMID | |||||||
| 関連識別子 | 30568951 | |||||||
| 出版社DOI | ||||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.12998/wjcc.v6.i15.952 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
