| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2021-04-26 |
| タイトル |
|
|
タイトル |
Detection of pancreatic ductal adenocarcinoma and liver metastases: comparison of Gd-EOB-DTPA-enhanced MR imaging vs. extracellular contrast materials |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Magnetic Resonance Imaging |
| キーワード |
|
|
主題 |
Pancreatic Cancer |
| キーワード |
|
|
主題 |
Metastasis |
| キーワード |
|
|
主題 |
Contrast Materials |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Noda, Yoshifumi
Goshima, Satoshi
Takai, Yukiko
Kawai, Nobuyuki
Kawada, Hiroshi
Tanahashi, Yukichi
Matsuo, Masayuki
|
| 書誌情報 |
Abdominal radiology
巻 45,
号 8,
p. 2459-2468,
発行日 2020-08
|
| 出版者 |
|
|
出版者 |
Springer Nature |
| 権利 |
|
|
権利情報 |
" This is a post-peer-review, pre-copyedit version of an article published in ""Abdominal radiology"". The final authenticated version is available online at: https://doi.org/10.1007/s00261-020-02511-9. " |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: To compare the detectability of PDAC and liver metastases between Gd-EOB-DTPA- and extracellular contrast materials (ECCMs) contrast-enhanced MR imaging contrast.
Methods: Two hundred seventy-two patients with suspected pancreatic disease underwent Gd-EOB-DTPA-enhanced MR imaging (EOB group, n=79) or ECCMs-enhanced MR imaging (ECCM group, n=193). The ECCM group were administered the following contrast agents: Gd-DTPA (n=158), Gd-BT-DO3A (n=28), Gd-DOTA (n=5), and Gd-DTPA-BMA (n=2). Signal intensities of pancreatic parenchyma, paraspinal muscle, PDAC (if present), and background noise were measured. The signal intensity ratio (SIR) of the pancreas and tumor-to-pancreas contrast-to-noise ratio (CNR) were also calculated. If present, the conspicuity of PDAC was evaluated with the arterial dominant phase images. Liver metastases, if present, were also evaluated for all sequences. Qualitative and quantitative imaging parameters were compared between EOB and ECCM groups.
Results: SIR of the pancreas (P<0.001) and CNR (P=0.0037) were significantly lower in EOB group when compared with the ECCM group. However, the sensitivity (97.1% vs. 93.5%, P=0.42) and specificity (100.0% vs. 99.2%, P=1.00) for detecting PDAC were not significant between EOB and ECCM groups. The EOB group showed a significantly greater sensitivity for detecting liver metastases compared with the ECCM group (95.0% vs 84.5%, P=0.04) when evaluating on a lesion-by-lesion basis.
Conclusions: Gd-EOB-DTPA-enhanced MR imaging performed similarly to ECCMs-enhanced MR imaging in detecting PDAC but had better sensitivity in detecting liver metastases. |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2366-004X |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2366-0058 |
| PubMed番号 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
32248260 |
| 出版社DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s00261-020-02511-9 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
AbdomRaiol-45-2459.pdf (1.2 MB)
