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Optimal plane selection for measuring post-prandial blood flow increase within the superior mesenteric artery: Analysis using 4D flow and computational fluid dynamics
http://hdl.handle.net/10271/00003854
http://hdl.handle.net/10271/000038544c8fcee4-747d-4c91-a20d-ed18a53d92aa
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
論文本文 (3.9 MB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||
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| 公開日 | 2021-05-10 | |||||||
| タイトル | ||||||||
| タイトル | Optimal plane selection for measuring post-prandial blood flow increase within the superior mesenteric artery: Analysis using 4D flow and computational fluid dynamics | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題 | 4D Flow | |||||||
| キーワード | ||||||||
| 主題 | phase contrast image | |||||||
| キーワード | ||||||||
| 主題 | superior mesenteric artery | |||||||
| キーワード | ||||||||
| 主題 | flow measurement | |||||||
| キーワード | ||||||||
| 主題 | post-prandial hyperemia | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||
| 資源タイプ | doctoral thesis | |||||||
| アクセス権 | ||||||||
| アクセス権 | open access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||
| その他のタイトル | ||||||||
| その他のタイトル | 食事負荷後の上腸間膜動脈の血流増加を測定するのに最適な断面の選択: 4D Flowと計算流体力学を用いた解析 | |||||||
| 著者 |
杉山, 将隆
× 杉山, 将隆
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| 書誌情報 |
en : Magnetic Resonance in Medical Sciences 巻 19, 号 4, p. 366-374, 発行日 2020 |
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| 出版者 | ||||||||
| 出版者 | Japanese Society for Magnetic Resonance in Medicine | |||||||
| 言語 | en | |||||||
| 権利 | ||||||||
| 言語 | en | |||||||
| 権利情報 | Copyright 2020. Japanese Society for Magnetic Resonance in Medicine | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Purpose: 2D cine phase contrast (PC)-MRI is a standard velocimetry for the superior mesenteric artery (SMA); however, the optimal localization of the measurement plane has never been fully discussed previously. The purpose of this Institutional Review Board approved prospective and single arm study is to test whether flow velocimetry of the SMA with combined use of 2D cine PC-MRI and meal challenge is dependent on the localizations of the measurement planes and to seek optimal section for velocimetry. Methods: Seven healthy volunteers underwent cardiac phase resolved ECG gated 2D cine PC-MRI pre- and 30 min post-meal challenge at three measurement planes: proximal, curved mid section and distal straight section of the SMA at 3T. 4D Flow using 3D cine PC-MRI with vastly undersampled isotropic projection imaging (PC VIPR) was also performed right after 2D cine PC-MRI to delineate the flow dynamics within the SMA using streamline analysis. Two radiologists measured flow velocities, and rated the appearances of the abnormal flow in the SMA on streamlines derived from the 4D Flow and the computational fluid dynamics (CFD). Results: 2D cine PC-MRI measured increased temporally averaged flow velocity (mm/s) after the meal challenge only in the proximal (129.3 vs. 97.8, P=0.0313) and distal section (166.9 vs. 96.2, P=0.0313), not in the curved mid section (113.1 vs. 85.5, P=0.0625). The average velocities were highest and their standard errors (8.5?26.5) were smallest at the distal straight section both before and after the meal challenge as compared with other sections. The streamline analysis depicted more frequent appearances of vertical or helical flow in the curved mid section both on 4D Flow and CFD (κ: 0.27?0.68). Conclusion: SMA velocimetry with 2D cine PC-MRI was dependent on the localization of the measurement planes. Distal straight section, not in the curved mid section is recommended for MR velocimetry. |
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| 言語 | en | |||||||
| 学位名 | ||||||||
| 学位名 | 博士（医学） | |||||||
| 学位の区分 | ||||||||
| 内容記述 | doctoral | |||||||
| 学位の分野 | ||||||||
| 内容記述 | 医学系研究科 | |||||||
| 学位授与機関 | ||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||
| 学位授与機関識別子 | 13802 | |||||||
| 学位授与機関名 | 浜松医科大学 | |||||||
| 学位授与年月日 | ||||||||
| 学位授与年月日 | 2020-10-16 | |||||||
| 学位授与番号 | ||||||||
| 学位授与番号 | 甲第847号 | |||||||
| ISSN | ||||||||
| 収録物識別子タイプ | PISSN | |||||||
| 収録物識別子 | 1347-3182 | |||||||
| EISSN | ||||||||
| 収録物識別子タイプ | EISSN | |||||||
| 収録物識別子 | 1880-2206 | |||||||
| PubMed番号 | ||||||||
| 識別子タイプ | PMID | |||||||
| 関連識別子 | 32009062 | |||||||
| 出版社DOI | ||||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.2463/mrms.mp.2019-0089 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
