| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2021-08-20 |
| タイトル |
|
|
タイトル |
Time-domain reflectance diffuse optical tomography for imaging breast cancer |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Diffuse optical tomography |
| キーワード |
|
|
主題 |
time-domain |
| キーワード |
|
|
主題 |
hand-held probe |
| キーワード |
|
|
主題 |
breast cancer |
| キーワード |
|
|
主題 |
chemotherapy monitoring |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Yoshimoto, Kenji
Wada, Hiroko
Yoshizawa, Nobuko
Ogura, Hiroyuki
Ohmae, Etsuko
Suzuki, Hiroaki
Homma, Shu
Mimura, Tetsuya
Suzuki, Norihiro
Asano, Yuko
Goshima, Satoshi
Ueda, Yukio
|
| 書誌情報 |
Proceedings of SPIE : Optical Tomography and Spectroscopy of Tissue XIV
巻 11639,
p. 116391I,
発行日 2021-03-09
|
| 出版者 |
|
|
出版者 |
SPIE (The international society for optics and photonics) |
| 権利 |
|
|
権利情報 |
Copyright 2021. Society of Photo?Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this publication for a fee or for commercial purposes, and modification of the contents of the publication are prohibited. |
| 権利 |
|
|
権利情報 |
Author(s), “Time-domain reflectance diffuse optical tomography for imaging breast cancer”, Proc. SPIE 11639, Optical Tomography and Spectroscopy of Tissue XIV, 116391I (9 March 2021); https://doi.org/10.1117/12.2576597. |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We report a time-domain reflectance diffuse optical tomography (TD-RDOT) system for providing three-dimensional images of hemoglobin concentration, tissue oxygen saturation, water and lipid contents of breast cancer from reflectance measurements. A scan area of 5×5 grid points with a 10-mm spacing is marked on the breast surface so that the tumor is just below the center of the area. The breast scan is performed by measuring the temporal profiles of six wavelengths at each grid point using a time-domain diffuse optical spectroscopy (TD-DOS) system and a hand-held probe. The TD-DOS system that we developed is capable of measuring water and lipid contents and hemoglobin concentration. The hand-held probe is designed to measure the breast in reflectance mode with a source-to-detector separation of 20 mm. The three-dimensional distributions of the tissue parameters are restored using an iterative image reconstruction method. As a preliminary clinical demonstration, a breast cancer patient with a tumor size of approximately 20 mm was examined with the TD-RDOT. The reconstructed images show that the breast cancer had high hemoglobin concentration and water content, and low tissue oxygen saturation and lipid content. The results indicate that the TD-RDOT system has the potential to provide diagnostically relevant information on the tissue characteristics of the tumor at the bedside. |
| 注記 |
|
|
内容記述 |
Event: SPIE BiOS, 2021, Online Only
SPIE Photonics West |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0277-786X |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1996-756X |
| 出版社DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1117/12.2576597 |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
Proc. of SPIE-11639-116391I.pdf (611.2 kB)
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