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Histological Imaging of Gastric Tumors by Scanning Acoustic Microscope
http://hdl.handle.net/10271/00004079
http://hdl.handle.net/10271/00004079c68ce716-deb0-41de-805a-dbe093de7116
| 名前 / ファイル | ライセンス | アクション |
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BJAST-4-1.pdf (5.7 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
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| 公開日 | 2022-03-15 | |||||||||
| タイトル | ||||||||||
| タイトル | Histological Imaging of Gastric Tumors by Scanning Acoustic Microscope | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| キーワード | ||||||||||
| 主題 | Scanning acoustic microscope | |||||||||
| キーワード | ||||||||||
| 主題 | tissue elasticity | |||||||||
| キーワード | ||||||||||
| 主題 | cancer imaging | |||||||||
| キーワード | ||||||||||
| 主題 | gastric tumor | |||||||||
| キーワード | ||||||||||
| 主題 | fibrosis | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| 著者 |
Miura, Katsutoshi
× Miura, Katsutoshi
× Yamamoto, Seiji
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| 書誌情報 |
British Journal of Applied Science & Technology 巻 4, 号 1, p. 1-17, 発行日 2014-01 |
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| 出版者 | ||||||||||
| 出版者 | SCIENCEDOMAIN international | |||||||||
| 権利 | ||||||||||
| 権利情報 | © 2014 Miura and Yamamoto; This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Background: Human body tissues have their own speed-of-sound (SOS) by which sound travels through them. Harder materials exhibit greater SOS; thus, SOS through each tissue can provide information regarding its elasticity. For tumor discrimination in clinical medicine, palpation provides important information. However, manual palpation is subjective, whereas SOS data are objective and can be directly used to compare lesions. Methods: A scanning acoustic microscope (SAM) uses ultrasound to image an object from SOS through tissues. We investigated the utility of SAM in imaging gastrointestinal lesions. Results: We visualized the digestive tract as a layered structure and discriminated tumors to a degree comparable with that observed by light microscopy. Areas with greater SOS corresponded to those with higher collagen or muscle fiber concentrations. Cell-poor areas or regions with degeneration demonstrated less SOS than surrounding tissues. Gastric tumors displayed appropriate SOS similar to their original tissues and showed significant differences in SOS between scirrhous carcinomas and well-differentiated medullary carcinomas, scirrhous carcinomas and malignant lymphomas, and leiomyomas and leiomyosarcomas. Conclusions: SAM offered the following benefits over LM: (1) images are acquired in a few minutes without special staining; (2) repeated observations of the same section are possible; (3) high-resolution digital imaging from SOS is comparable to LM; (4) SAM analysis could be helpful in understanding endoscopic ultrasonography imaging; and (5) digitized SOS data could be statistically compared among different stomach lesions. |
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| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 2231-0843 | |||||||||
| 出版社DOI | ||||||||||
| 関連タイプ | isIdenticalTo | |||||||||
| 識別子タイプ | DOI | |||||||||
| 関連識別子 | 10.9734/BJAST/2014/5101 | |||||||||
| 著者版フラグ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
