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Application of Scanning Acoustic Microscopy to Pathological Diagnosis
http://hdl.handle.net/10271/00004081
http://hdl.handle.net/10271/00004081b4c062b4-57e2-4c46-bab3-917f696e13a8
| 名前 / ファイル | ライセンス | アクション |
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Microsc anal-381.pdf (53.5 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2022-03-16 | |||||||
| タイトル | ||||||||
| タイトル | Application of Scanning Acoustic Microscopy to Pathological Diagnosis | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 主題 | elasticity | |||||||
| キーワード | ||||||||
| 主題 | histochemistry | |||||||
| キーワード | ||||||||
| 主題 | imaging analysis | |||||||
| キーワード | ||||||||
| 主題 | protease | |||||||
| キーワード | ||||||||
| 主題 | scanning acoustic microscopy | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 著者 |
Miura, Katsutoshi
× Miura, Katsutoshi
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| 書誌情報 |
Microscopy and Analysis p. 381-401, 発行日 2016-09-21 |
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| 出版者 | ||||||||
| 出版者 | IntechOpen | |||||||
| 権利 | ||||||||
| 権利情報 | © 2016 The Author(s). Licensee InTech. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||||
| 抄録 | ||||||||
| 内容記述タイプ | Abstract | |||||||
| 内容記述 | Scanning acoustic microscopy (SAM) can obtain high-quality microscopic images of tissues and cells that are comparable with light microscopic images without staining and within only a few minutes. The speed of sound through tissues and cells is correlated with elasticity, thereby indicating their biomechanical properties. The elasticity varies according to the contents, such as collagen or elastic fibers, blood, colloids, mucin, ground substances, and cytoskeleton; therefore, SAM can follow changes in the composition of tissues and cells to determine their functions. Chemical modifications such as fixation, periodic acid-Schiff reaction, and enzymatic digestion may influence acoustic properties, and SAM can follow these changes over time in the same section to facilitate statistical comparisons based on digital values. Digital imaging using SAM is superior to analog methods for modifying images to discriminate changes, such as malignant and benign cell types. The observation ranges are shown in a colored column, and they can be manually adjusted. Thus, precise differences in acoustic properties are readily distinguished by narrowing the range. The resolution of SAM is determined by the wavelength, and it can theoretically exceed that of visible light. Combining these distinct techniques may help to elucidate the structural and functional characteristics of tissues and cells. | |||||||
| 注記 | ||||||||
| 内容記述 | Chapter 15 | |||||||
| ISBN | ||||||||
| 識別子タイプ | ISBN | |||||||
| 関連識別子 | 9789535125792 | |||||||
| 出版社DOI | ||||||||
| 関連タイプ | isIdenticalTo | |||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | 10.5772/63405 | |||||||
| 著者版フラグ | ||||||||
| 出版タイプ | VoR | |||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||
