| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2022-06-10 |
| タイトル |
|
|
タイトル |
Survival impact of perioperative changes in prognostic nutritional index levels after esophagectomy |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Esophageal cancer |
| キーワード |
|
|
主題 |
Esophagectomy |
| キーワード |
|
|
主題 |
Prognostic nutritional index |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Haneda, Ryoma
Hiramatsu, Yoshihiro
Kawata, Sanshiro
Honke, Junko
Soneda, Wataru
Matsumoto, Tomohiro
Morita, Yoshifumi
Kikuchi, Hirotoshi
Kamiya, Kinji
Takeuchi, Hiroya
|
| 書誌情報 |
Esophagus
巻 19,
号 2,
p. 250-259,
発行日 2022-04
|
| 出版者 |
|
|
出版者 |
Springer Nature |
| 出版者 |
|
|
出版者 |
日本食道学会 = The Japan Esophageal Society |
| 権利 |
|
|
権利情報 |
"The version of record of this article, first published in ""Esophagus"", is available online at Publisher’s website: http://dx.doi.org/10.1007/s10388-021-00883-5." |
| 権利 |
|
|
権利情報 |
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background The correlation between perioperative changes in nutritional status during esophagectomy and prognosis remains unclear. This study aimed to evaluate the impact of changes in prognostic nutritional index levels during the perioperative period on esophageal cancer patient survivals.
Methods From January 2009 to May 2019, 158 patients with esophageal squamous cell carcinoma were enrolled. From the time-dependent ROC analysis, the cutoff values of preoperative and postoperative prognostic nutritional index levels were 46.9 and 40.9. Patients were divided into preoperative-high group (Group H) and preoperative-low group (Group L). Then, patients in Group L were divided into preoperative-low and postoperative-high group (Group L?H) and preoperative-low and postoperative-low group (Group L?L). Long-term outcomes and prognostic factors were evaluated.
Results Patients in Group L had significantly worse overall survival than those in Group H (p=0.001). Patients in Group L?L had significantly worse overall survival than those in Group L?H (p=0.023). However, there was no significant difference in overall survival between Groups H and L?H (p=0.224). In multivariable analysis, advanced pathological stage (hazard ratio 10.947, 95% confidence interval 2.590?46.268, p=0.001) and Group L?L (hazard ratio 2.171, 95% confidence interval 1.249?3.775, p=0.006) were independent predictors of poor overall survival.
Conclusions Patients in Group L?H had a good prognosis, similar to those in Group H. This result indicated that increasing the postoperative prognostic nutritional index level sufficiently using various intensive perioperative support methods could improve prognosis after esophagectomy in patients with poor preoperative nutritional status. |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1612-9059 |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1612-9067 |
| PubMed番号 |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
34546503 |
| 出版社DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s11748-020-01374-7 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
Esophagus-19-250.pdf (1.2 MB)
.png)
