| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
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|
タイトル |
Ontogeny of plasma cells in the early rat yolk sac |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
HEMATOPOIETIC STEM-CELLS |
| キーワード |
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|
主題 |
COLONY-FORMING CELLS |
| キーワード |
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|
主題 |
IN-VITRO |
| キーワード |
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|
主題 |
B-CELLS |
| キーワード |
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|
主題 |
MOUSE EMBRYO |
| キーワード |
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|
主題 |
T-CELLS |
| キーワード |
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|
主題 |
DIFFERENTIATION |
| キーワード |
|
|
主題 |
MACROPHAGES |
| キーワード |
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|
主題 |
VIVO |
| キーワード |
|
|
主題 |
PROLIFERATION |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
El-Nefiawy, Nagwa
Abdel-Hakim, Khaled
Kanayama, Naohiro
Suganuma, Nobihiko
Terao, Toshihiko
|
| 書誌情報 |
en : Archives of Histology and Cytology
巻 66,
号 4,
p. 327-335,
発行日 2003-10
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| 出版者 |
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出版者 |
International Society of Histology and Cytology |
|
言語 |
en |
| 権利 |
|
|
権利情報 |
Copyright 2004 by International Society of Histology and Cytology |
| 権利 |
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|
権利情報 |
本文データは学協会の許諾に基づきJ-STAGEから複製したものである |
| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
The present study investigated the development of plasma cells in the early rat yolk sac (days 10-16 of gestation) by light microscopy, transmission electron microscopy, immunoelectron microscopy, and indirect immunofluoresce techniques. Cells delineating the morphology of plasma cells in the yolk sac were observed as early as 12 days of embryonic life. As for positive immune staining for the intra-cyto-plasmic immunoglobulin (Ig) production (IgA, IgM and IgG), the intensity of the immune staining was very weak on days 10 and 11 of gestation, while it turned very dense on day 12 of gestation. At 14 days of gestation, the number of positive cells was markedly reduced. Immunoelectron microscopy visualized products of the immune reaction in cisterns of the rough endoplasmic reticulum. Conventional electron microscopic examination of 12, 13, and 16-day yolk sacs confirmed the development and differentiation of plasma cells with their well-known ultrastructural features, making this the first study to demonstrate these in the early rat yolk sac. The development of plasma cells in the early yolk sac implies the ability of the yolk sac to effect a humoral immune response at this stage of fetal life. The probable role of plasma cells in the yolk sac is also discussed. |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
09149465 |
| EISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
13491717 |
| 出版社DOI |
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|
関連タイプ |
isIdenticalTo |
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|
識別子タイプ |
DOI |
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関連識別子 |
10.1679/aohc.66.327 |
| 著者版フラグ |
|
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出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
archives of h and c-66-327.pdf (5.0 MB)
