| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
Application of thermoresponsive HPLC to forensic toxicology: determination of barbiturates in human urine |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Thermoresponsive polymer column |
| キーワード |
|
|
主題 |
Temperature-responsive |
| キーワード |
|
|
主題 |
Barbiturates |
| キーワード |
|
|
主題 |
Phenobarbital |
| キーワード |
|
|
主題 |
HPLC |
| キーワード |
|
|
主題 |
Human urine |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Kanno, Sanae
Watanabe, Kanako
Hirano, Seishiro
Yamagishi, Itaru
Gonmori, Kunio
Minakata, Kayoko
Suzuki, Osamu
|
| 書誌情報 |
en : Forensic Toxicology
巻 27,
号 2,
p. 103-106,
発行日 2009-07-01
|
| 出版者 |
|
|
出版者 |
Springer |
|
言語 |
en |
| 権利 |
|
|
権利情報 |
Copyright Japanese Association of Forensic Toxicology and Springer 2009 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
A high-performance liquid chromatography (HPLC) method has been developed for the assays of five barbiturates in human urine using a new thermoresponsive polymer separation column, which is composed of N-isopropylacrylamide polymer. According to elevating the column temperature from 10 ℃ to 50 ℃, five barbiturates, such as metharbital, primidone, phenobarbital, mephobarbital and pentobarbital, became well separated by this method. Five barbiturates showed good linearity in the range of 0.2-10 mg/ml. Good accuracy, precision and recoveries for these drugs were obtained at 1 and 5 μg/ml urine. The method with the new-type column seems to have high potential to be extensively used in forensic toxicology for analysis of many drugs and poisons by HPLC and HPLC-mass spectrometry (MS) (-MS). |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
18608965 |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
18608973 |
| 出版社DOI |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1007/s11419-009-0076-z |
| 著者版フラグ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
Forensic_T-27-103.pdf (208.2 kB)
