WEKO3
アイテム
{"_buckets": {"deposit": "12108ac3-890b-402e-9a35-72edfda84e7b"}, "_deposit": {"created_by": 4, "id": "1869", "owners": [4], "pid": {"revision_id": 0, "type": "depid", "value": "1869"}, "status": "published"}, "_oai": {"id": "oai:hama-med.repo.nii.ac.jp:00001869", "sets": ["11"]}, "author_link": ["4715", "4716", "4717", "4718", "4719"], "item_3_biblio_info_5": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-09-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "25", "bibliographicPageEnd": "2629", "bibliographicPageStart": "2624", "bibliographicVolumeNumber": "877", "bibliographic_titles": [{"bibliographic_title": "Journal of Chromatography B", "bibliographic_titleLang": "en"}]}]}, "item_3_description_30": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_3_description_9": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Inorganic arsenic species are metabolized to monomethylarsonic acid (MMA V) and dimethylarsinic acid (DMA V) and excreted into urine. A simple, rapid and sensitive method has been developed using electrospray ionization tandem mass spectrometry (ESI-MS-MS) for the simultaneous determination of MMA V and DMA V. MMA V and DMA V in a sample were allowed to react with citric acid (CiA). Adduct compounds were extracted together with isoamyl alcohol (IAA). An aliquot (1-μL) of the IAA layer was directly injected into the ESI-MS-MS instrument, and was detected within 1 min. Quantification was done using selected reaction monitoring for MMA V and DMA V as follows. [MMAH + 2CiA - 3H2O]+ → [MMAH + CiA - 2H2O]+ [DMAH + CiA + MeOH - 2H2O]+ → [DMAH + MeOH - H2O]+ Where, MMAH and DMAH denote the protonated forms of MMA V and DMA V, and MeOH denotes methanol (carrier liquid in ESI-MS-MS). This method was validated for the analysis of urine samples. The limit of detection of As was 0.3 μgL-1 for MMA V and 0.6 μgL-1 for DMA V using 10 μL of sample solution. Results were obtained in \u003c10 min with a linear calibration range of 3-100 μgL-1. Inorganic arsenic compounds (and other organic arsenic compounds) found in urine did not interfere with the detection of MMA V and DMA V. Concentrations of MMA V and DMA V in the reference urine SRM 2670a were estimated after partial purification, and those in urine of a patient treated with As2O3 were measured after dilution.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_3_publisher_6": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier", "subitem_publisher_language": "en"}]}, "item_3_relation_28": {"attribute_name": "出版社DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.jchromb.2009.03.016", "subitem_relation_type_select": "DOI"}}]}, "item_3_rights_7": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright 2009 Elsevier B.V.", "subitem_rights_language": "en"}]}, "item_3_select_2": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_select_item": "Journal Article", "subitem_select_language": "en"}]}, "item_3_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "15700232", "subitem_source_identifier_type": "ISSN"}]}, "item_3_version_type_32": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Minakata, Kayoko", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4715", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohnishi, Kazunori", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4716", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamura, Satoki", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4717", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Masako", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4718", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Suzuki, Osamu", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4719", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-08-27"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "JofC_B-877-2624.pdf", "filesize": [{"value": "517.4 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 517400.0, "url": {"label": "JofC_B-877-2624.pdf", "url": "https://hama-med.repo.nii.ac.jp/record/1869/files/JofC_B-877-2624.pdf"}, "version_id": "ad8796f8-ee0a-47de-b248-ee2acb2ff423"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Monomethylarsonic acid", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Dimethylarsinic acid", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Tandem mass spectrometry", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Electrospray ionization", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Citric acid", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Adduct", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid", "subitem_title_language": "en"}]}, "item_type_id": "3", "owner": "4", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10271/1902", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2013-08-27"}, "publish_date": "2013-08-27", "publish_status": "0", "recid": "1869", "relation": {}, "relation_version_is_last": true, "title": ["Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid"], "weko_shared_id": -1}
Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid
http://hdl.handle.net/10271/1902
http://hdl.handle.net/10271/19026fbc65d5-52b1-4e0d-bace-6b10e27924f0
名前 / ファイル | ライセンス | アクション |
---|---|---|
JofC_B-877-2624.pdf (517.4 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2013-08-27 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Electrospray ionization tandem mass spectrometric determination of monomethylarsonic acid and dimethylarsinic acid after adduct formation with citric acid | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Monomethylarsonic acid | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Dimethylarsinic acid | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Tandem mass spectrometry | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Electrospray ionization | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Citric acid | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Adduct | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Minakata, Kayoko
× Minakata, Kayoko× Ohnishi, Kazunori× Nakamura, Satoki× Suzuki, Masako× Suzuki, Osamu |
|||||
書誌情報 |
en : Journal of Chromatography B 巻 877, 号 25, p. 2624-2629, 発行日 2009-09-01 |
|||||
出版者 | ||||||
言語 | en | |||||
出版者 | Elsevier | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Copyright 2009 Elsevier B.V. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Inorganic arsenic species are metabolized to monomethylarsonic acid (MMA V) and dimethylarsinic acid (DMA V) and excreted into urine. A simple, rapid and sensitive method has been developed using electrospray ionization tandem mass spectrometry (ESI-MS-MS) for the simultaneous determination of MMA V and DMA V. MMA V and DMA V in a sample were allowed to react with citric acid (CiA). Adduct compounds were extracted together with isoamyl alcohol (IAA). An aliquot (1-μL) of the IAA layer was directly injected into the ESI-MS-MS instrument, and was detected within 1 min. Quantification was done using selected reaction monitoring for MMA V and DMA V as follows. [MMAH + 2CiA - 3H2O]+ → [MMAH + CiA - 2H2O]+ [DMAH + CiA + MeOH - 2H2O]+ → [DMAH + MeOH - H2O]+ Where, MMAH and DMAH denote the protonated forms of MMA V and DMA V, and MeOH denotes methanol (carrier liquid in ESI-MS-MS). This method was validated for the analysis of urine samples. The limit of detection of As was 0.3 μgL-1 for MMA V and 0.6 μgL-1 for DMA V using 10 μL of sample solution. Results were obtained in <10 min with a linear calibration range of 3-100 μgL-1. Inorganic arsenic compounds (and other organic arsenic compounds) found in urine did not interfere with the detection of MMA V and DMA V. Concentrations of MMA V and DMA V in the reference urine SRM 2670a were estimated after partial purification, and those in urine of a patient treated with As2O3 were measured after dilution. | |||||
言語 | en | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15700232 | |||||
出版社DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.jchromb.2009.03.016 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa |