{"_buckets": {"deposit": "3cc40091-3fd6-4a2b-a018-c43c2ce04b1a"}, "_deposit": {"created_by": 4, "id": "2349", "owners": [4], "pid": {"revision_id": 0, "type": "depid", "value": "2349"}, "status": "published"}, "_oai": {"id": "oai:hama-med.repo.nii.ac.jp:00002349", "sets": ["11"]}, "author_link": [], "item_3_biblio_info_5": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-02-23", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8", "bibliographicPageEnd": "2025", "bibliographicPageStart": "2020", "bibliographicVolumeNumber": "28", "bibliographic_titles": [{"bibliographic_title": "Vaccine"}]}]}, "item_3_description_30": {"attribute_name": "フォーマット", "attribute_value_mlt": [{"subitem_description": "application/pdf", "subitem_description_type": "Other"}]}, "item_3_description_9": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Mycobacterial DNA-binding protein 1 (MDP1) is a major protein antigen in mycobacteria and induces protective immunity against Mycobacterium tuberculosis infection in mice. In this study we determined murine T-cell epitopes on MDP1 with MDP1 DNA immunization in mice. We analyzed interferon-γ production from the MDP1 DNA-immune splenocytes in response to 20-mer overlapping peptides covering MDP1 protein. We identified several CD4+ T-cell epitopes in three inbred mouse strains and one CD8+ T-cell epitope in C57BL/6 mice. These T-cell epitopes would be feasible for analysis of the role of MDP1-specific T-cells in protective immunity and for future vaccine design against M. tuberculosis infection.", "subitem_description_type": "Abstract"}]}, "item_3_publisher_6": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_3_relation_28": {"attribute_name": "出版社DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.vaccine.2009.10.062", "subitem_relation_type_select": "DOI"}}]}, "item_3_rights_7": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright 2009 Elsevier Ltd"}]}, "item_3_select_2": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"subitem_select_item": "Journal Article", "subitem_select_language": "en"}]}, "item_3_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0264410X", "subitem_source_identifier_type": "ISSN"}]}, "item_3_version_type_32": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Suzuki, Daisuke"}]}, {"creatorNames": [{"creatorName": "Nagata, Toshi"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Sohkichi"}]}, {"creatorNames": [{"creatorName": "Matsumoto, Makoto"}]}, {"creatorNames": [{"creatorName": "Tsujimura, Kunio"}]}, {"creatorNames": [{"creatorName": "Koide, Yukio"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2018-08-27"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Vaccine28_6-2020.pdf", "filesize": [{"value": "249.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 249300.0, "url": {"label": "Vaccine28_6-2020.pdf", "url": "https://hama-med.repo.nii.ac.jp/record/2349/files/Vaccine28_6-2020.pdf"}, "version_id": "73c40234-e4d5-4195-8611-bc4c56d1a47b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "DNA immunization", "subitem_subject_scheme": "Other"}, {"subitem_subject": "T-cell epitope", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Mycobacterium tuberculosis", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination", "subitem_title_language": "en"}]}, "item_type_id": "3", "owner": "4", "path": ["11"], "permalink_uri": "http://hdl.handle.net/10271/2406", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2013-08-27"}, "publish_date": "2013-08-27", "publish_status": "0", "recid": "2349", "relation": {}, "relation_version_is_last": true, "title": ["Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination"], "weko_shared_id": -1}
Characterization of murine T-cell epitopes on mycobacterial DNA-binding protein 1 (MDP1) using DNA vaccination
http://hdl.handle.net/10271/2406
http://hdl.handle.net/10271/2406