| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2013-08-27 |
| タイトル |
|
|
タイトル |
Intracellular Sodium Concentration in Diabetic Rat Ventricular Myocytes |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
Sodium-binding benzofuran isophthalate (SBFI) |
| キーワード |
|
|
主題 |
Hexamethylene amiloride |
| キーワード |
|
|
主題 |
Streptozotocin |
| キーワード |
|
|
主題 |
Diabetes mellitus |
| キーワード |
|
|
主題 |
Sodium hydrogen exchange |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Katoh, Hideki
Noda, Naohisa
Hayashi, Hideharu
Satoh, Hiroshi
Terada, Hajime
Ohno, Ryuzo
Yamazaki, Noboru
|
| 書誌情報 |
Japanese Heart Journal
巻 36,
号 5,
p. 647-656,
発行日 1995-05-08
|
| 出版者 |
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|
出版者 |
International Heart Journal Association |
| 権利 |
|
|
権利情報 |
by International Heart Journal Association |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
We measured intracellular Na+ concentration ([Na+]i) of diabetic rat ventricular myocytes using sodium-binding benzofuran isophthalate (SBFI). We used diabetic rats at 8 weeks after the injection of streptozotocin (45mg/kg i.v.). The level of [Na+]i during the control perfusion was significantly lower in diabetic myocytes than that in normal myocytes (9.2±0.4mM v.s. 12.0±0.3 mM, p<0.01). After the 40min perfusion of 1μM hexamethylene amiloride (HMA), [Na+]i decreased significantly in both groups. However, there was no difference in [Na+]i between the two groups after the perfusion of HMA. It was suggested that the lower [Na+]i in diabetic myocytes could be due to the decreased activity of Na+/H+ exchange system. (Jpn Heart J 36: 647-656, 1995) |
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
00214868 |
| EISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1348673X |
| 出版社DOI |
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|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.1536/ihj.36.647 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
JHeartJ-36-647.pdf (618.2 kB)
